@article{fdi:010078000,
  title = {{E}ffect of ion doping in silica-based nanoparticles on the hemolytic and oxidative activity in contact with human erythrocytes},
  author = {{T}samesidis, {I}. and {P}ouroutzidou, {G}. {K}. and {L}ymperaki, {E}. and {K}azeli, {K}. and {L}ioutas, {C}. {B}. and {C}hristodoulou, {E}. and {P}erio, {P}ierre and {R}eybier, {K}. and {P}antaleo, {A}. and {K}ontonasaki, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}im: {T}he aim of this study was the synthesis of ion doped silica-based nanoparticles and the evaluation of their toxic effect on erythrocytes. {M}aterials & methods: {T}heir synthesis was performed using the sol-gel method, by the progressive addition of calcium, magnesium and copper ions on pure silica nanoparticles. {T}he toxicity evaluation was based on hemolysis, lipid peroxidation, {ROS}, {H}2{O}2 species and antioxidant enzyme production. {R}esults: {T}he addition of {M}g and {C}u in the {SN}s presented better hemocompatibility by protecting erythrocytes from oxidative stress. {C}onclusion: {I}on doping with magnesium in the investigated calcium silicate system induces a protective effect in erythrocyte membrane in compare with pure silica nanoparticles.},
  keywords = {{S}ilica-based nanoparticles ; {I}on doping ; {E}rythrocytes ; {O}xidative stress},
  booktitle = {},
  journal = {{C}hemico-{B}iological {I}nteractions},
  volume = {318},
  numero = {},
  pages = {art. 108974 [10 p.]},
  ISSN = {0009-2797},
  year = {2020},
  DOI = {10.1016/j.cbi.2020.108974},
  URL = {https://www.documentation.ird.fr/hor/fdi:010078000},
}