Characterization of ESBL-producing enterobacteria from fruit bats in an unprotected area of Makokou, Gabon [+ Correction] Nguema P. P. M. auteur aut IRD Onanga R. auteur aut IRD Atome G. R. N. auteur aut IRD Mbeang J. C. O. auteur aut IRD Mabika A. M. auteur aut IRD Yaro M. auteur aut IRD Lounnas Manon auteur aut IRD Dumont Y. auteur aut IRD Zohra Z. F. auteur aut IRD Godreuil S. auteur aut IRD Bretagnolle F. auteur aut IRD text journalArticle eng text/pdf reformatted digital access In Gabon, terrestrial mammals of protected areas have been identified as a possible source of antibiotic-resistant bacteria. Some studies on antibiotic resistance in bats have already been carried out. The main goal of our study was to detect extended-spectrum beta-lactamases (ESBLs) that are produced by enterobacteria from bats in the Makokou region in Gabon. Sixty-eight fecal samples were obtained from 68 bats caught in the forests located 1 km from the little town of Makokou. After culture and isolation, 66 Gram-negative bacterial colonies were obtained. The double-disk diffusion test confirmed the presence of ESBLs in six (20.69%) Escherichia coli isolates, four (13.79%) Klebsiella pneumoniae isolates, and one (3.45%) Enterobacter cloacae isolate. The analysis based on the nucleotide sequences of the ESBL resistance genes showed that all cefotaximase-Munichs (CTX-Ms) were CTX-M-15 and that all sulfhydryl variables (SHVs) were SHV-11: 41.67% CTX-M-15-producing E. coli, 16.67% CTX-M-15+SHV-11-producing E. coli, 8.33% CTX-M-15-producing K. pneumoniae, 25% CTX-M-15+SHV-11-producing K. pneumoniae, and 8.33% CTX-M-15-produced E. cloacae. This study shows for the first time the presence of multiresistant ESBL-producing enterobacteria in fruit bats in Makokou. specialized bats Gram-negative bacteria ESBL multiresistance reservoir GABON 080 084 Microorganisms 8 1 art. 138 [15 ] [+ Correction, 2020, vol.8, no 9, art. 1384] 2020 https://www.documentation.ird.fr/hor/fdi:010077967 10.3390/microorganisms8010138 [F B010077967] https://www.documentation.ird.fr/hor/fdi:010077967 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-04/010077967.pdf IRD - Base Horizon / Pleins textes 2020-05-18 2026-07-21 fdi:010077967 fre