%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Nguema, P. P. M.
%A Onanga, R.
%A Atome, G. R. N.
%A Mbeang, J. C. O.
%A Mabika, A. M.
%A Yaro, M.
%A Lounnas, Manon
%A Dumont, Y.
%A Zohra, Z. F.
%A Godreuil, S.
%A Bretagnolle, F.
%T Characterization of ESBL-producing enterobacteria from fruit bats in an unprotected area of Makokou, Gabon [+ Correction in : Microorganisms, 2020, vol.8, no 9, art. 1384]
%D 2020
%L fdi:010077967
%G ENG
%J Microorganisms
%K bats ; Gram-negative bacteria ; ESBL ; multiresistance ; reservoir
%K GABON
%K MAKOKOU
%M ISI:000514650700052
%N 1
%P art. 138 [15  + Correction in : Microorganisms, 2020, vol.8, no 9, art. 1384]
%R 10.3390/microorganisms8010138
%U https://www.documentation.ird.fr/hor/fdi:010077967
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-04/010077967.pdf
%V 8
%W Horizon (IRD)
%X In Gabon, terrestrial mammals of protected areas have been identified as a possible source of antibiotic-resistant bacteria. Some studies on antibiotic resistance in bats have already been carried out. The main goal of our study was to detect extended-spectrum beta-lactamases (ESBLs) that are produced by enterobacteria from bats in the Makokou region in Gabon. Sixty-eight fecal samples were obtained from 68 bats caught in the forests located 1 km from the little town of Makokou. After culture and isolation, 66 Gram-negative bacterial colonies were obtained. The double-disk diffusion test confirmed the presence of ESBLs in six (20.69%) Escherichia coli isolates, four (13.79%) Klebsiella pneumoniae isolates, and one (3.45%) Enterobacter cloacae isolate. The analysis based on the nucleotide sequences of the ESBL resistance genes showed that all cefotaximase-Munichs (CTX-Ms) were CTX-M-15 and that all sulfhydryl variables (SHVs) were SHV-11: 41.67% CTX-M-15-producing E. coli, 16.67% CTX-M-15+SHV-11-producing E. coli, 8.33% CTX-M-15-producing K. pneumoniae, 25% CTX-M-15+SHV-11-producing K. pneumoniae, and 8.33% CTX-M-15-produced E. cloacae. This study shows for the first time the presence of multiresistant ESBL-producing enterobacteria in fruit bats in Makokou.
%$ 080 ; 084