@article{fdi:010077966, title = {{B}roader geographical distribution of {T}oscana virus in the {M}editerranean region suggests the existence of larger varieties of sand fly vectors}, author = {{A}yhan, {N}azli and {P}rudhomme, {J}. and {L}aroche, {L}. and {B}anuls, {A}nne-{L}aure and {C}harrel, {R}. {N}.}, editor = {}, language = {{ENG}}, abstract = {{T}oscana virus ({TOSV}) is endemic in the {M}editerranean basin, where it is transmitted by sand flies. {TOSV} can infect humans and cause febrile illness as well as neuroinvasive infections affecting the central and peripheral nervous systems. {A}lthough {TOSV} is a significant human pathogen, it remains neglected and there are consequently many gaps of knowledge. {R}ecent seroepidemiology studies and case reports showed that {TOSV}'s geographic distribution is much wider than was assumed a decade ago. {T}he apparent extension of the {TOSV} circulation area raises the question of the sandfly species that are able to transmit the virus in natural conditions. {P}hlebotomus ({P}h.) perniciosus and {P}h. perfiliewi were historically identified as competent species. {R}ecent results suggest that other species of sand flies could be competent for {TOSV} maintenance and transmission. {H}ere we organize current knowledge in entomology, epidemiology, and virology supporting the possible existence of additional phlebotomine species such as {P}h. longicuspis, {P}h. sergenti, {P}h. tobbi, {P}h. neglectus, and {S}ergentomyia minuta in {TOSV} maintenance. {W}e also highlight some of the knowledge gaps to be addressed in future studies.}, keywords = {{ZONE} {MEDITERRANEENNE} ; {T}oscana virus ; sand fly ; {P}hlebotomus ; {S}ergentomyia ; {M}editerranean area ; {P}henuiviridae ; {B}unyavirales ; {S}andfly fever {N}aples phlebovirus ; arbovirus ; arthropod-borne ; sandfly ; phlebotomine ; {ITALIE} ; {ESPAGNE} ; {FRANCE} ; {PORTUGAL} ; {TURQUIE} ; {CHYPRE} ; {GRECE} ; {CROATIE} ; {BOSNIE} {HERZEGOVINE} ; {BULGARIE} ; {TUNISIE} ; {MAROC} ; {ALGERIE} ; {KOSOVO}}, booktitle = {}, journal = {{M}icroorganisms}, volume = {8}, numero = {1}, pages = {114 [11]}, year = {2020}, DOI = {10.3390/microorganisms8010114}, URL = {https://www.documentation.ird.fr/hor/fdi:010077966}, }