%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Grison, C. %A Carrasco, David %A Pelissier, F. %A Moderc, A. %T Reflexion on bio-sourced mosquito repellents : nature, activity, and preparation %D 2020 %L fdi:010077962 %G ENG %J Frontiers in Ecology and Evolution %@ 2296-701X %K mosquito ; bio-sourced repellent ; essential oil ; synergy ; chemosensation %M ISI:000517173900001 %P art. 8 [14 ] %R 10.3389/fevo.2020.00008 %U https://www.documentation.ird.fr/hor/fdi:010077962 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers20-04/010077962.pdf %V 8 %W Horizon (IRD) %X Over the last decades, the geographical distribution of certain mosquito species carrying vector-borne diseases has considerably expanded. They represent a major health concern as they transmit pathogens causing alarming epidemics. In the absence of vaccines for most of the mosquito-borne diseases, the use of topical mosquito repellents is one of the main measures to prevent human-mosquito contacts. Synthetic repellents are the most used mosquito repellents. However, several concerns about their safety for consumers have led to a growing demand of natural alternatives. Here we present an overview of the most commonly used natural-based mosquito repellents: repellent activity, biological action, composition, stereochemical structure (when appropriate) and syntheses, paradoxically far from being eco-friendly. We discuss on future prospective that would combine sustainable chemical processes and synergistic effects promising for the development of natural, safe and efficient topical repellents. %$ 052 ; 020