@article{fdi:010077856,
  title = {{R}are and unique adaptations to cancer in domesticated species : an untapped resource ?},
  author = {{T}homas, {F}. and {G}iraudeau, {M}. and {D}heilly, {N}. {M}. and {G}ouzerh, {F}. and {B}outry, {J}. and {B}eckmann, {C}. and {B}iro, {P}. {A}. and {H}amede, {R}. and {A}badie, {J}. and {L}abrut, {S}. and {B}ieuville, {M}. and {M}iss{\'e}, {D}oroth{\'e}e and {B}ramwell, {G}. and {S}chultz, {A}. and {L}e {L}oc'h, {G}. and {V}incze, {O}. and {R}oche, {B}enjamin and {R}enaud, {F}. and {R}ussell, {T}. and {U}jvari, {B}.},
  editor = {},
  language = {{ENG}},
  abstract = {{S}trong and ongoing artificial selection in domestic animals has resulted in amazing phenotypic responses that benefit humans, but often at a cost to an animal's health, and problems related to inbreeding depression, including a higher incidence of cancer. {D}espite high rates of cancer in domesticated species, little attention has been devoted to exploring the hypothesis that persistent artificial selection may also favour the evolution of compensatory anticancer defences. {I}ndeed, there is evidence for effective anti-cancer defences found in several domesticated species associated with different cancer types. {W}e also suggest that artificial selection can favour the "domestication" of inherited oncogenic mutations in rare instances, retaining those associated to late and/or less aggressive cancers, and that by studying these seemingly rare anticancer adaptations, novel cancer treatments may be found.},
  keywords = {cancer ; domestication ; domestication syndrome ; evolution ; evolutionary ; mismatch ; selection},
  booktitle = {},
  journal = {{E}volutionary {A}pplications},
  volume = {13},
  numero = {7},
  pages = {1605--1614},
  ISSN = {1752-4571},
  year = {2020},
  DOI = {10.1111/eva.12920},
  URL = {https://www.documentation.ird.fr/hor/fdi:010077856},
}