@article{fdi:010077837,
  title = {{D}ual analysis of loss to follow-up for perinatally {HIV}-infected adolescents receiving combination antiretroviral therapy in {A}sia},
  author = {{B}artlett, {A}. {W}. and {L}umbiganon, {P}. and {M}ohamed, {T}. {A}. {J}. and {L}apphra, {K}. and {M}uktiarti, {D}. and {D}u, {Q}. {T}. and {H}ansudewechakul, {R}. and {L}y, {P}. {S}. and {T}ruong, {K}. {H}. and {N}guyen, {L}. {V}. and {P}uthanakit, {T}. and {S}udjaritruk, {T}. and {C}hokephaibulkit, {K}. and {D}o, {V}. {C}. and {K}umarasamy, {N}. and {Y}usoff, {N}. {K}. {N}. and {K}urniati, {N}. and {F}ong, {M}. {S}. and {W}ati, {D}. {K}. and {N}allusamy, {R}. and {S}ohn, {A}. {H}. and {K}ariminia, {A}. and {K}hol, {V}. and {T}ucker, {J}. and {E}zhilarasi, {C}. and {K}inikar, {A}. and {M}ave, {V}. and {N}imkar, {S}. and {V}edaswari, {D}. and {R}amajaya, {I}. {B}. and {F}ong, {S}. {M}. and {L}im, {M}. and {D}aut, {F}. and {M}ohamad, {P}. and {M}ohamed, {T}. {J}. and {D}rawis, {M}. {R}. and {C}han, {K}. {C}. and {S}irisanthana, {V}. and {A}urpibul, {L}. and {O}unchanum, {P}. and {D}enjanta, {S}. and {K}ongphonoi, {A}. and {K}osalaraksa, {P}. and {T}harnprisan, {P}. and {U}domphanit, {T}. and {J}ourdain, {G}onzague and {A}nugulruengkit, {S}. and {J}antarabenjakul, {W}. and {N}adsasarn, {R}. and {P}hongsamart, {W}. and {S}richaroenchai, {S}. and {N}guyen, {C}. {H}. and {H}a, {T}. {M}. and {K}hu, {D}. {T}. {K}. and {P}ham, {A}. {N}. and {N}guyen, {L}. {T}. and {L}e, {O}. {N}. and {R}oss, {J}. {L}. and {S}uwanlerk, {T}. and {L}aw, {M}. {G}. and {TREAT} {A}sia {P}ediatric {HIV} {O}bservational {D}atabase of {I}e{DEA} {A}sia-{P}acific},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {P}erinatally {HIV}-infected adolescents ({PHIVA}) are an expanding population vulnerable to loss to follow-up ({LTFU}). {U}nderstanding the epidemiology and factors for {LTFU} is complicated by varying {LTFU} definitions. {S}etting: {A}sian regional cohort incorporating 16 pediatric {HIV} services across 6 countries. {M}ethods: {D}ata from {PHIVA} (aged 10-19 years) who received combination antiretroviral therapy 2007-2016 were used to analyze {LTFU} through (1) an {I}nternational epidemiology {D}atabases to {E}valuate {AIDS} ({I}e{DEA}) method that determined {LTFU} as >90 days late for an estimated next scheduled appointment without returning to care and (2) the absence of patient-level data for >365 days before the last data transfer from clinic sites. {D}escriptive analyses and competing-risk survival and regression analyses were used to evaluate {LTFU} epidemiology and associated factors when analyzed using each method. {R}esults: {O}f 3509 included {PHIVA}, 275 (7.8%) met {I}e{DEA} and 149 (4.3%) met 365-day absence {LTFU} criteria. {C}umulative incidence of {LTFU} was 19.9% and 11.8% using {I}e{DEA} and 365-day absence criteria, respectively. {R}isk factors for {LTFU} across both criteria included the following: age at combination antiretroviral therapy initiation <5 years compared with age >= 5 years, rural clinic settings compared with urban clinic settings, and high viral loads compared with undetectable viral loads. {A}ge 10-14 years compared with age 15-19 years was another risk factor identified using 365-day absence criteria but not {I}e{DEA} {LTFU} criteria. {C}onclusions: {B}etween 12% and 20% of {PHIVA} were determined {LTFU} with treatment fatigue and rural treatment settings consistent risk factors. {B}etter tracking of adolescents is required to provide a definitive understanding of {LTFU} and optimize evidence-based models of care.},
  keywords = {{HIV} ; adolescent ; loss to follow-up ; {CAMBODGE} ; {INDE} ; {INDONESIE} ; {MALAISIE} ; {THAILANDE} ; {VIET} {NAM}},
  booktitle = {},
  journal = {{JAIDS}},
  volume = {82},
  numero = {5},
  pages = {431--438},
  ISSN = {1525-4135},
  year = {2019},
  DOI = {10.1097/qai.0000000000002184},
  URL = {https://www.documentation.ird.fr/hor/fdi:010077837},
}