Structural characterization and anti-infective activity of 9,10-seco-29-norcycloartane glycosides isolated from the flowers of the Peruvian medicinal plant Cordia lutea Castro, I. Fabre, N. /Bourgeade-Delmas, Sandra Saffon, N. Gandini, C. /Sauvain, Michel Castillo, D. /Bourdy, Geneviève /Jullian, Valérie Six new secocycloartane glycosides (1-6) were isolated from the ethanol extract of the flowers of Cordia lutea Lam. on the basis of bioassay-guided fractionation. Their structures were determined by the application of NMR and MS data analyses together with X-ray crystallographic analyses for compounds 1 and 2. Compounds 1-6 represent the first examples of 9,10-seco-29-norcycloartane glycosides. These compounds showed significant in vitro anti-Helicobacter pylori activity, and no activity against either Escherichia coli or Pseudomonas aeruginosa. Significant activity was observed for 5 and 6 against Staphylococcus aureus. All compounds displayed weak cytotoxicity against RAW 264.7 cells. The in vitro antileishmanial and antiplasmodial activities of 1-6 were also evaluated. 2019 text https://www.documentation.ird.fr/hor/fdi:010077493 fdi:010077493 Castro I., Fabre N., Bourgeade-Delmas Sandra, Saffon N., Gandini C., Sauvain Michel, Castillo D., Bourdy Geneviève, Jullian Valérie. Structural characterization and anti-infective activity of 9,10-seco-29-norcycloartane glycosides isolated from the flowers of the Peruvian medicinal plant Cordia lutea. 2019, 82 (12), 3233-3241 EN PEROU