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    <titleInfo>
      <title>Lactobacillus plantarum P2R3FA isolated from traditional cereal-based fermented food increase folate status in deficient rats</title>
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    <abstract>Folate deficiencies are widespread around the world. Promoting consumption of folate-rich foods could be a sustainable option to alleviate this problem. However, these foods are not always available. Cereals, being a staple food, could contribute to folate intake. They are fermented prior to consumption in many African countries, and fermentation can modify the folate content. In Ethiopia, injera is a widely consumed fermented flat bread. The main drivers of its fermentation are lactic acid bacteria (LAB). The aim of this work was to isolate and identify folate-producing LAB from injera fermented dough and to evaluate their ability to increase folate status after depletion in a rat model. Among the 162 strains isolated from 60 different fermentations, 19 were able to grow on a folate-free culture medium and produced 1 to 43 mu g/L (24 h, 30 degrees C incubation). The four highest folate producers belonged to the Lactobacillus plantarum species. The most productive strain was able to enhance folate status after depletion in a rat model, despite the relatively low folate content of the feed supplemented with the strain. Folate-producing L. plantarum strain has potential use as a commercial starter in injera production.</abstract>
    <targetAudience authority="marctarget">specialized</targetAudience>
    <subject>
      <topic>bioavailability</topic>
      <topic>cereal</topic>
      <topic>fermentation</topic>
      <topic>folate</topic>
      <topic>lactic acid bacteria rats</topic>
    </subject>
    <subject authority="local">
      <geographic>ETHIOPIE</geographic>
    </subject>
    <classification authority="local">054</classification>
    <classification authority="local">080</classification>
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      <titleInfo>
        <title>Nutrients</title>
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      <part>
        <detail type="volume">
          <number>11</number>
        </detail>
        <detail type="volume">
          <number>11</number>
        </detail>
        <extent unit="pages">
          <list> art. 2819 [11 p.]</list>
        </extent>
      </part>
      <originInfo>
        <dateIssued>2019</dateIssued>
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    <identifier type="uri">https://www.documentation.ird.fr/hor/fdi:010077469</identifier>
    <identifier type="doi">10.3390/nu11112819</identifier>
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      <url usage="primary display" access="object in context">https://www.documentation.ird.fr/hor/fdi:010077469</url>
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      <recordCreationDate encoding="w3cdtf">2020-02-05</recordCreationDate>
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