@article{fdi:010077416,
  title = {{I}mmune trypanolysis test as a promising bioassay to monitor the elimination of gambiense human {A}frican trypanosomiasis},
  author = {{D}ama, {E}. and {C}amara, {O}. and {K}aba, {D}. and {K}offi, {M}. and {C}amara, {M}. and {C}ompaore, {C}. and {I}lboudo, {H}. and {C}ourtin, {F}abrice and {K}abore, {J}. and {N}'{G}ouan, {E}. {K}. and {B}uscher, {P}. and {L}ejon, {V}eerle and {B}ucheton, {B}runo and {J}amonneau, {V}incent},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he {W}orld {H}ealth {O}rganization ({WHO}) has set the goal of gambiense-{H}uman {A}frican trypanosomiasis ({HAT}) elimination as a public health problem for 2020 and interruption of transmission in humans for 2030. {I}n this context, it is crucial to monitor progress towards these targets using accurate tools to assess the level of transmission in a given area. {T}he aim of this study was to investigate the relevance of the immune trypanolysis test ({TL}) as a population-based bioassay to evaluate {T}rypanosoma brucei gambiense transmission in various epidemiological contexts. {S}ignificant correlations were observed between {HAT} endemicity levels and the percentage of {TL}-positive individuals in the population. {TL} therefore appears to be a suitable population-based biomarker of the intensity of transmission. {I}n addition to being used as a tool to assess the {HAT} status at an individual level, assessing the proportion of {TL} positive individuals in the population appears as a promising and easy alternative to monitor the elimination of gambiense {HAT} in a given area.},
  keywords = {{H}uman {A}frican {T}rypanosomiasis ; {T}rypanosoma brucei gambiense ; {E}limination ; {D}iagnosis ; {T}ransmission ; {I}mmune trypanolysis ; {AFRIQUE} {SUBSAHARIENNE} ; {COTE} {D}'{IVOIRE} ; {BURKINA} {FASO} ; {GUINEE}},
  booktitle = {},
  journal = {{P}arasite},
  volume = {26},
  numero = {},
  pages = {art. 68 [7 ]},
  ISSN = {1252-607{X}},
  year = {2019},
  DOI = {10.1051/parasite/2019066},
  URL = {https://www.documentation.ird.fr/hor/fdi:010077416},
}