Excito-repellent activity of beta-caryophyllene oxide against Aedes aegypti and Anopheles minimus Nararak, J. Sathantriphop, S. Kongmee, M. Mahiou-Leddet, V. Ollivier, E. /Manguin, Sylvie Chareonviriyaphap, T. Aedes aegypti Anopheles minimus beta-Caryophyllene oxide Contact irritancy Non-contact repellency Contact irritant and non-contact repellent activities of beta-caryophyllene oxide were evaluated against laboratory strains of female Aedes aegypti (USDA strain), a major arbovirus vector and Anopheles minimus (KU strain), a major malaria parasite vector, compared with the synthetic repellent DEET, using an excito-repellency test system. beta-caryophyllene oxide and DEET were tested at concentrations of 0.1, 0.25, 0.5 and 1.0% (v/v). Anopheles minimus was found to be more sensitive to beta-caryophyllene oxide than that of Ae. aegypti and exhibited high avoidance response rates (86-96% escape) at 0.5% and 1.0% concentrations in contact and non-contact trials compared with Ae. aegypti (22-59% escape). However, at the same concentrations, DEET displayed lower irritancy and repellency capacities against these two mosquito species (range 0-54% escape) compared to beta-aryophyllene oxide. The analysis of escape responses showed significant differences between mosquito species at all concentrations (P < 0.05) except for 0.1%. For both species, there were significant differences in irritant and repellent responses between beta-caryophyllene oxide and DEET at higher concentrations (0.5 and 1.0%). 2019 text https://www.documentation.ird.fr/hor/fdi:010077388 fdi:010077388 Nararak J., Sathantriphop S., Kongmee M., Mahiou-Leddet V., Ollivier E., Manguin Sylvie, Chareonviriyaphap T.. Excito-repellent activity of beta-caryophyllene oxide against Aedes aegypti and Anopheles minimus. 2019, 197, art. 105030 [8 p.] EN