@article{fdi:010077341,
  title = {{D}iversity of dromedary camel coronavirus {HKU}23 in {A}frican camels revealed multiple recombination events among closely related betacoronaviruses of the subgenus {E}mbecovirus},
  author = {{S}o, {R}. {T}. {Y}. and {C}hu, {D}. {K}. {W}. and {M}iguel, {E}ve and {P}erera, {R}apm and {O}ladipo, {J}. {O}. and {F}assi-{F}ihri, {O}. and {A}ylet, {G}. and {K}o, {R}. {L}. {W}. and {Z}hou, {Z}. {Q}. and {C}heng, {M}. {S}. and {K}uranga, {S}. {A}. and {R}oger, {F}. {L}. and {C}hevalier, {V}. and {W}ebby, {R}. {J}. and {W}oo, {P}. {C}. {Y}. and {P}oon, {L}. {L}. {M}. and {P}eiris, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{G}enetic recombination has frequently been observed in coronaviruses. {H}ere, we sequenced multiple complete genomes of dromedary camel coronavirus {HKU}23 ({D}c{C}o{V}-{HKU}23) from {N}igeria, {M}orocco, and {E}thiopia and identified several genomic positions indicative of cross-species virus recombination events among other betacoronaviruses of the subgenus {E}mbecovirus ({G}lade {A} beta-{C}o{V}s). {R}ecombinant fragments of a rabbit coronavirus ({R}b{C}o{V}-{HKU}14) were identified at the hemagglutinin esterase gene position. {H}omolog fragments of a rodent {C}o{V} were also observed at 8.9-k{D}a open reading frame 4a at the 3' end of the spike gene. {T}he patterns of recombination differed geographically across the {A}frican region, highlighting a mosaic structure of {D}c{C}o{V}-{HKU}23 genomes circulating in dromedaries. {O}ur results highlighted active recombination of coronaviruses circulating in dromedaries and are also relevant to the emergence and evolution of other betacoronaviruses, including {M}iddle {E}ast respiratory syndrome coronavirus ({MERS}-{C}o{V}). {IMPORTANCE} {G}enetic recombination is often demonstrated in coronaviruses and can result in host range expansion or alteration in tissue tropism. {H}ere, we showed interspecies events of recombination of an endemic dromedary camel coronavirus, {HKU}23, with other {G}lade {A} betacoronaviruses. {O}ur results supported the possibility that the zoonotic pathogen {MERS}-{C}o{V}, which also cocirculates in the same camel species, may have undergone similar recombination events facilitating its emergence or may do so in its future evolution.},
  keywords = {coronaviruses ; betacoronaviruses ; recombination ; phylogeny ; dromedary ; camels ; evolution ; {NIGERIA} ; {ETHIOPIE} ; {MAROC} ; {AFRIQUE} {DE} l'{OUEST} ; {AFRIQUE} {DE} l'{EST} ; {AFRIQUE} {DU} {NORD}},
  booktitle = {},
  journal = {{J}ournal of {V}irology},
  volume = {93},
  numero = {23},
  pages = {e01236--19 [18 p.]},
  ISSN = {0022-538{X}},
  year = {2019},
  DOI = {10.1128/jvi.01236-19},
  URL = {https://www.documentation.ird.fr/hor/fdi:010077341},
}