@article{fdi:010077173, title = {{G}ambian human {A}frican trypanosomiasis in {N}orth {W}est {U}ganda. {A}re we on course for the 2020 target ?}, author = {{S}elby, {R}. and {W}amboga, {C}. and {E}rphas, {O}. and {M}ugenyi, {A}. and {J}amonneau, {V}incent and {W}aiswa, {C}. and {T}orr, {S}. {J}. and {L}ehane, {M}.}, editor = {}, language = {{ENG}}, abstract = {{I}n 1994, combined active and passive screening reported 1469 cases from the historic {G}ambian {H}uman {A}frican {T}rypanosomiasis (g{HAT}) foci of {W}est {N}ile, {U}ganda. {S}ince 2011 systematic active screening has stopped and there has been reliance on passive screening. {D}uring 2014, passive screening alone detected just nine cases. {I}n the same year a tsetse control intervention was expanded to cover the main g{HAT} foci in {W}est {N}ile to curtail transmission of g{HAT} contributing to the elimination of g{HAT} as a public health problem in the area. {I}t is known that sole reliance on passive screening is slow to detect cases and can underestimate the actual true number. {W}e therefore undertook an active screening programme designed to test the efficacy of these interventions against g{HAT} transmission and clarify disease status. {S}creening was conducted in 28 randomly selected villages throughout the study area, aiming to sample all residents. {W}hole blood from 10,963 participants was analysed using {CATT} and 97 {CATT} suspects (0.9%) were evaluated with microscopy and trypanolysis. {N}o confirmed cases were found providing evidence that the g{HAT} prevention programmes in {W}est {N}ile have been effective. {R}esults confirm g{HAT} prevalence in the study area of {W}est {N}ile is below the elimination threshold (1 new case / 10,000 population), making elimination on course across this study area if status is maintained. {T}he findings of this study can be used to guide future {HAT} and tsetse management in other g{HAT} foci, where reduced caseloads necessitate a shift from active to passive screening.}, keywords = {{OUGANDA}}, booktitle = {}, journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases}, volume = {13}, numero = {8}, pages = {e0007550 [15 p.]}, ISSN = {1935-2735}, year = {2019}, DOI = {10.1371/journal.pntd.0007550}, URL = {https://www.documentation.ird.fr/hor/fdi:010077173}, }