@article{fdi:010077159, title = {{S}patial assessment of contact between humans and {A}nopheles and {A}edes {M}osquitoes in a medium-sized {A}frican urban setting, using salivary antibody-based biomarkers}, author = {{S}agna, {A}. {B}. and {K}assie, {D}. and {C}ouvray, {A}. and {A}dja, {A}. {M}. and {H}ermann, {E}. and {R}iveau, {G}. and {S}alem, {G}. and {F}ournet, {F}lorence and {R}emou{\'e}, {F}ranck}, editor = {}, language = {{ENG}}, abstract = {{B}ackground. {A}narchic and poorly controlled urbanization led to an increased risk of mosquito-borne diseases ({MBD}) in many {A}frican cities. {H}ere, we evaluate the spatial heterogeneity of human exposure to malaria and arboviral disease vectors in an urban area of northern {S}enegal, using antibody-based biomarkers of exposure to {A}nopheles and {A}edes mosquito bites. {M}ethods. {A} cross-sectional study was undertaken during the rainy season of 2014 in 4 neighborhoods of {S}aint-{L}ouis, a city in northern {S}enegal. {A}mong children aged 6-59 months in each neighborhood, the dried blood spot technique was used to evaluate immunoglobulin {G} ({I}g{G}) responses to both g{SG}6-{P}1 ({A}nopheles) and {N}term-34-k{D}a ({A}edes) salivary peptides as validated biomarkers of respective mosquito bite exposure. {R}esults. {I}g{G} response levels to g{SG}6-{P}1 and {N}term-34-k{D}a salivary peptides varied significantly between the 4 neighborhoods ({P} <.0001). {T}he level of exposure to {A}edes bites also varied according to household access to sanitation services ({P} .027), whereas that of exposure to {A}nopheles bites varied according to insecticide-treated bed net use ({P} .006). {I}n addition, spatial clusters of high contact between humans and mosquitoes were identified inside 3 neighborhoods. {C}onclusions. {A}ntibody-based biomarkers of exposure to {A}nopheles and {A}edes mosquito bites could be helpful tools for evaluating the heterogeneity of exposure to malaria and arboviral disease vectors by national control programs.}, keywords = {{U}rban area ; salivary biomarkers ; g{SG}6-{P}1 ; {A}nopheles ; {N}term-34-k{D} ; {A}edes ; {MBD} risk ; {SENEGAL} ; {SAINT} {LOUIS}}, booktitle = {}, journal = {{J}ournal of {I}nfectious {D}iseases}, volume = {220}, numero = {7}, pages = {1199--1208}, ISSN = {0022-1899}, year = {2019}, DOI = {10.1093/infdis/jiz289}, URL = {https://www.documentation.ird.fr/hor/fdi:010077159}, }