@article{fdi:010077061,
  title = {{N}atural {W}olbachia infections are common in the major malaria vectors in {C}entral {A}frica},
  author = {{A}yala, {D}iego and {A}kone-{E}lla, {O}. and {R}ahola, {N}il and {K}engne, {P}ierre and {N}gangue, {M}. {F}. and {M}ezeme, {F}. and {M}akanga, {B}. {K}. and {N}igg, {M}artha and {C}ostantini, {C}arlo and {S}imard, {F}r{\'e}d{\'e}ric and {P}rugnolle, {F}. and {R}oche, {B}enjamin and {D}uron, {O}. and {P}aupy, {C}hristophe},
  editor = {},
  language = {{ENG}},
  abstract = {{D}uring the last decade, the endosymbiont bacterium {W}olbachia has emerged as a biological tool for vector disease control. {H}owever, for long time, it was believed that {W}olbachia was absent in natural populations of {A}nopheles. {T}he recent discovery that species within the {A}nopheles gambiae complex host {W}olbachia in natural conditions has opened new opportunities for malaria control research in {A}frica. {H}ere, we investigated the prevalence and diversity of {W}olbachia infection in 25 {A}frican {A}nopheles species in {G}abon ({C}entral {A}frica). {O}ur results revealed the presence of {W}olbachia in 16 of these species, including the major malaria vectors in this area. {T}he infection prevalence varied greatly among species, confirming that sample size is a key factor to detect the infection. {M}oreover, our sequencing and phylogenetic analyses showed the important diversity of {W}olbachia strains that infect {A}nopheles. {C}o-evolutionary analysis unveiled patterns of {W}olbachia transmission within some {A}nopheles species, suggesting that past independent acquisition events were followed by co-cladogenesis. {T}he large diversity of {W}olbachia strains that infect natural populations of {A}nopheles offers a promising opportunity to select suitable phenotypes for suppressing {P}lasmodium transmission and/or manipulating {A}nopheles reproduction, which in turn could be used to reduce the malaria burden in {A}frica.},
  keywords = {{A}nopheles ; co-evolution ; disease control ; diversity ; {W}olbachia ; {GABON}},
  booktitle = {},
  journal = {{E}volutionary {A}pplications},
  volume = {12},
  numero = {8},
  pages = {1583--1594},
  ISSN = {1752-4571},
  year = {2019},
  DOI = {10.1111/eva.12804},
  URL = {https://www.documentation.ird.fr/hor/fdi:010077061},
}