@article{fdi:010077041, title = {{O}n hepatocellular carcinoma in {S}outh {A}merica and early-age onset of the disease}, author = {{P}ineau, {P}. and {R}uiz, {E}. and {D}eharo, {E}ric and {B}ertani, {S}t{\'e}phane}, editor = {}, language = {{ENG}}, abstract = {{H}epatocellular carcinoma ({HCC}) is one of the most predominant tumor types worldwide, being particularly prevalent in sub-{S}aharan {A}frica and {E}ast {A}sia. {H}owever, {HCC} is inexplicably underreported in {S}outh {A}merica, despite unsettling clinical epidemiological trends of the disease on this continent. {H}ere, we review the current knowledge on {HCC} presentation in {P}eru. {W}e emphasize the well-documented occurrence of an early-age nosological form of the disease in {A}ndean descent populations. {W}e further discuss the reasons for such {HCC} clinical presentation, as well as the implications for liver cancer screening, management, and prevention.}, keywords = {{L}iver cancer ; {C}ancer risk factor ; {H}epatitis {B} virus ({HBV}) ; {I}ndigenous people ; {L}ow- and middle-income countries ; {G}lobal health transition ; {PEROU} ; {ANDES}}, booktitle = {}, journal = {{C}linics and {R}esearch in {H}epatology and {G}astroenterology}, volume = {43}, numero = {5}, pages = {522--526}, ISSN = {2210-7401}, year = {2019}, DOI = {10.1016/j.clinre.2018.10.019}, URL = {https://www.documentation.ird.fr/hor/fdi:010077041}, }