Dihydrohymenialdisines, new pyrrole-2-aminoimidazole alkaloids from the marine sponge Cymbastela cantharella [plus Supplementary data] Sauleau P. auteur aut IRD Retailleau P. auteur aut IRD Nogues S. auteur aut IRD Carletti I. auteur aut IRD Marcourt L. auteur aut IRD Raux R. auteur aut IRD Al Mourabit A. auteur aut IRD Debitus Cécile auteur aut IRD text journalArticle eng text/pdf born digital access In our investigation of bioactive marine natural products, we revisited an ethanolic extract of the New Caledonian sponge Cymbastela cantharella. Four new natural compounds (3-6) were isolated and their structural determinations as dihydrohymenialdisine derivatives were achieved by spectral data analysis and chemical conversion. These products did not show any activity in the Polo Like kinase bioassay, demonstrating thus the importance of the unique structure of hymenialdisine, known as an improved kinase inhibitor. specialized NOUVELLE CALEDONIE 035 Tetrahedron Letters 52 21 2676-2678 [+ 10 p.] 2011 0040-4039 https://www.documentation.ird.fr/hor/fdi:010076703 10.1016/j.tetlet.2011.03.073 0040-4039 [F b010076703] https://www.documentation.ird.fr/hor/fdi:010076703 https://www.documentation.ird.fr/intranet/publi/depot/2019-08-19/010076703.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2019-08-16 2019-08-20 fdi:010076703 fre