@article{fdi:010076641,
  title = {{A} decade decoded : spies and hackers in the history of {TAL} effectors research},
  author = {{P}erez-{Q}uintero, {A}. {L}. and {S}zurek, {B}oris},
  editor = {},
  language = {{ENG}},
  abstract = {{T}ranscription activator-like effectors ({TALE}s) from the genus {X}anthomonas are proteins with the remarkable ability to directly bind the promoters of genes in the plant host to induce their expression, which often helps bacterial colonization. {M}etaphorically, {TALE}s act as spies that infiltrate the plant disguised as high-ranking civilians (transcription factors) to trick the plant into activating weak points that allow an invasion. {C}urrent knowledge of how {TALE}s operate allows researchers to predict their activity (counterespionage) and exploit their function, engineering them to do our bidding (a {M}anchurian agent). {T}his has been possible thanks particularly to the discovery of their {DNA} binding mechanism, which obeys specific amino acid-{DNA} correspondences (the {TALE} code). {H}ere, we review the history of how researchers discovered the way these proteins work and what has changed in the ten years since the discovery of the code. {R}ecommended music for reading this review can be found in the {S}upplemental {M}aterial.},
  keywords = {{TAL} effectors ; {X}anthomonas ; history ; evolution ; biotechnology ; {BACTERIAL}-{BLIGHT}-{RESISTANCE} ; {CAMPESTRIS} {PV} {VESICATORIA} ; {TRANSCRIPTIONAL} ; {ACTIVATION} {DOMAIN} ; {DISEASE}-{SUSCEPTIBILITY} {GENE} ; {XANTHOMONAS}-{ORYZAE} {PV} ; {DNA}-{BINDING} ; {AVIRULENCE} {GENE} ; {PLANT} {PATHOGEN} ; {RALSTONIA}-{SOLANACEARUM} ; {PROTEIN} {AVRBS}3},
  booktitle = {},
  journal = {{A}nnual {R}eview of {P}hytopathology},
  volume = {57},
  numero = {},
  pages = {459--481},
  year = {2019},
  DOI = {10.1146/annurev-phyto-082718-100026},
  ISBN = {978-0-8243-1357-9},
  URL = {https://www.documentation.ird.fr/hor/fdi:010076641},
}