@article{fdi:010076577,
  title = {{N}asal or throat sampling is adequate for the detection of the human respiratory syncytial virus in children with acute respiratory infections},
  author = {{N}guyen, {V}. {H}. and {R}usse, {F}. {M}. and {D}ance, {D}. {A}. {B}. and {V}ilivong, {K}. and {P}hommachan, {S}. and {S}yladeth, {C}. and {L}ai, {J}. and {L}im, {R}. and {M}orpeth, {M}. and {M}ayxay, {M}. and {N}ewton, {P}. {N}. and {L}amballerie, {X}. de and {D}ubot {P}{\'e}r{\`e}s, {A}udrey},
  editor = {},
  language = {{ENG}},
  abstract = {{H}uman respiratory syncytial virus ({HRSV}) is one of the most important causes of acute respiratory infections ({ARI}) in young children. {HRSV} diagnosis is based on the detection of the virus in respiratory specimens. {N}asopharyngeal swabbing is considered the preferred method of sampling, although there is limited evidence of the superiority of nasopharyngeal swabs ({NPS}) over the less invasive nasal ({NS}) and throat ({TS}) swabs for virus detection by real-time reverse transcription quantitative polymerase chain reaction ({RT}-q{PCR}). {I}n the current study, we compared the three swabbing methods for the detection of {HRSV} by {RT}-q{PCR} in children hospitalized with {ARI} at {M}ahosot {H}ospital, {V}ientiane, {L}aos. {I}n 2014, {NS}, {NPS}, and {TS} were collected from 288 children. {A}ll three samples were tested for {HRSV} by {RT}-q{PCR}; 141 patients were found positive for at least one sample. {A}lmost perfect agreements (kappa > 0.8) between the swabs, compared two by two, were observed. {D}etection rates for the three swabs (between 93% and 95%) were not significantly different, regardless of the clinical presentation. {O}ur findings suggest that the uncomfortable and technically more demanding {NPS} method is not mandatory for {HRSV} detection by {RT}-q{PCR}.},
  keywords = {detection rate ; human respiratory syncytial virus ; {L}aos ; nasal swab ; nasopharyngeal swab ; throat swab ; {LAOS} ; {VIENTIANE}},
  booktitle = {},
  journal = {{J}ournal of {M}edical {V}irology},
  volume = {91},
  numero = {9},
  pages = {1602--1607},
  ISSN = {0146-6615},
  year = {2019},
  DOI = {10.1002/jmv.25496},
  URL = {https://www.documentation.ird.fr/hor/fdi:010076577},
}