@article{fdi:010076158,
  title = {{G}ut microbiota alteration is characterized by a {P}roteobacteria and {F}usobacteria bloom in kwashiorkor and a {B}acteroidetes paucity in {M}arasmus [article r{\'e}tract{\'e}]},
  author = {{P}ham, {T}. {P}. {T}. and {A}lou, {M}. {T}. and {B}echar, {D}. and {L}evasseur, {A}. and {B}rah, {S}. and {A}lhousseini, {D}. and {S}okhna, {C}heikh and {D}iallo, {A}. and {W}ieringa, {F}ranck and {M}illion, {M}. and {R}aoult, {D}.},
  editor = {},
  language = {{ENG}},
  abstract = {{K}washiorkor and marasmus are considered to be two different clinical diseases resulting from severe malnutrition, but this distinction has been questioned. {I}n a previous study comparing children with kwashiorkor and healthy children from {N}iger and {S}enegal, we found a dramatic gut microbiota alteration with a predominant depletion of anaerobes and enrichment in {P}roteobacteria and {F}usobacteria in kwashiorkor. {H}owever, it remained unknown whether this association was related to malnutrition or was a specific feature of kwashiorkor. {I}n this continuation study, we added 7 new marasmus subjects and 71,162 new colonies from the same countries. {O}ur results showed that, compared to marasmus, the kwashiorkor gut microbiota was characterized by an increased proportion of {P}roteobacteria (culturomics, {M}arasmus 5.0%, {K}washiorkor 16.7%, p < 0.0001; metagenomics, {M}arasmus 14.7%, {K}washiorkor 22.0%, p = 0.001), but there was a decreased proportion of {B}acteroidetes in marasmus (culturomics, {M}arasmus 0.8%, {K}washiorkor 6.5%, p = 0.001; metagenomics, {M}arasmus 5.4%, {K}washiorkor 7.0%, p = 0.03). {F}usobacterium was more frequently cultured from kwashiorkor. {A}ll detected potential pathogenic species were enriched in the kwashiorkor gut microbiota. {T}hese results provide a biological basis to support the usage of an antibiotic therapy more effective in suppressing the overgrowth of bacterial communities resistant to penicillin, combined with antioxidants and probiotics for nutritional recovery therapies, particularly for kwashiorkor.},
  keywords = {{SENEGAL} ; {NIGER}},
  booktitle = {},
  journal = {{S}cientific {R}eports - {N}ature},
  volume = {9},
  numero = {},
  pages = {9084 [13  + r{\'e}tractation : 2023, 13, 18590, 1 p.]},
  ISSN = {2045-2322},
  year = {2019},
  DOI = {10.1038/s41598-019-45611-3},
  URL = {https://www.documentation.ird.fr/hor/fdi:010076158},
}