%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Fritz, M. %A Taty, R. T. %A Portella, C. %A Guimbi, C. %A Mankou, M. %A Leroy, Eric %A Becquart, Pierre %T Re-emergence of chikungunya in the Republic of the Congo in 2019 associated with a possible vector-host switch %D 2019 %L fdi:010076125 %G ENG %J International Journal of Infectious Diseases %@ 1201-9712 %K Chikungunya ; Virus ; Outbreak ; Republic of the Congo ; Central Africa ; Aedes albopictus %K CONGO %M ISI:000471238000018 %P 99-101 %R 10.1016/j.ijid.2019.05.013 %U https://www.documentation.ird.fr/hor/fdi:010076125 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers19-07/010076125.pdf %V 84 %W Horizon (IRD) %X In January 2019, an outbreak of chikungunya virus fever was reported in a rural region near Pointe-Noire, Republic of the Congo. Molecular and phylogenetic analysis of this new CHIKV strain demonstrated the presence of the A226V substitution and a surprisingly close relation with Aedes aegypti-associated Central Africa chikungunya strains. These results, combined with the preponderance of Aedes albopictus in the outbreak area, suggest a recent vector-host switch facilitated by the emergence and spread of the A226V mutation from a related CHIKV strain previously circulating in Aedes aegypti. The proximity of this outbreak to the large city of Pointe-Noire alerts us to a possibly devastating future outbreak in the absence of measures limiting the proliferation of Ae. albopictus mosquitoes. %$ 052 ; 050