@article{fdi:010075751,
  title = {{M}osquito microevolution drives {P}lasmodium falciparum dynamics},
  author = {{G}ildenhard, {M}. and {R}ono, {E}. {K}. and {D}iarra, {A}. and {B}oissiere, {A}. and {B}ascunan, {P}. and {C}arrillo-{B}ustamante, {P}. and {C}amara, {D}. and {K}ruger, {H}. and {M}ariko, {M}. and {M}ariko, {R}. and {M}ireji, {P}. and {N}sango, {S}. {E}. and {P}ompon, {J}ulien and {R}eis, {Y}. and {R}ono, {M}. {K}. and {S}edan, {P}. {B}. and {T}hailayil, {J}. and {T}raore, {A}. and {Y}apto, {C}. {V}. and {A}wono-{A}mbene, {P}. and {D}abire, {R}. {K}. and {D}iabate, {A}. and {M}asiga, {D}. and {C}atteruccia, {F}. and {M}orlais, {I}sabelle and {D}iallo, {M}. and {S}angare, {D}. and {L}evashina, {E}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}alaria, a major cause of child mortality in {A}frica, is engendered by {P}lasmodium parasites that are transmitted by anopheline mosquitoes. {F}itness of {P}lasmodium parasites is closely linked to the ecology and evolution of its anopheline vector. {H}owever, whether the genetic structure of vector populations impacts malaria transmission remains unknown. {H}ere, we describe a partitioning of the {A}frican malaria vectors into generalists and specialists that evolve along ecological boundaries. {W}e next identify the contribution of mosquito species to {P}lasmodium abundance using {G}ranger causality tests for time-series data collected over two rainy seasons in {M}ali. {W}e find that mosquito microevolution, defined by changes in the genetic structure of a population over short ecological timescales, drives {P}lasmodium dynamics in nature, whereas vector abundance, infection prevalence, temperature and rain have low predictive values. {O}ur study demonstrates the power of time-series approaches in vector biology and highlights the importance of focusing local vector control strategies on mosquito species that drive malaria dynamics.},
  keywords = {{MALI} ; {BURKINA} {FASO} ; {KENYA} ; {CAMEROUN}},
  booktitle = {},
  journal = {{N}ature {M}icrobiology},
  volume = {4},
  numero = {6},
  pages = {941--947},
  ISSN = {2058-5276},
  year = {2019},
  DOI = {10.1038/s41564-019-0414-9},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075751},
}