Mulatier Margaux auteur aut IRD Camara S. auteur aut IRD Koffi A. auteur aut IRD Carrasco David auteur aut IRD Porciani Angélique auteur aut IRD Chandre Fabrice auteur aut IRD Moiroux Nicolas auteur aut IRD Lefèvre Thierry auteur aut IRD Dabiré R. auteur aut IRD Assi S. auteur aut IRD Alou L. P. A. auteur aut IRD Dormont L. auteur aut IRD Pennetier Cédric auteur aut IRD Cohuet Anna auteur aut IRD text journalArticle eng text/pdf reformatted digital access Within mosquito vector populations, infectious mosquitoes are the ones completing the transmission of pathogens to susceptible hosts and they are, consequently, of great epidemiological interest. Mosquito infection by malaria parasites has been shown to affect several traits of mosquito physiology and behavior, and could interplay with the efficacy of control tools. In this study, we evaluated, in pyrethroid resistant Anopheles gambiae, the effect of mosquito infection with the human malaria parasite Plasmodium falciparum on the efficacy of nets treated with either the insecticide deltamethrin or the repellent DEET, measuring (i) mosquito success to pass through the net, (ii) blood-feeding on a host and (iii) chemicals-induced mortality. Infection of mosquitoes at non-infectious stage did not affect their success to pass through the net, to blood-feed, nor chemicals-induced mortality. At infectious stage, depending on replicates, infected mosquitoes had higher mortality rates than uninfected mosquitoes, with stronger effect in presence of DEET. This data evidenced a cost of infection on mosquito survival at transmissible stages of infection, which could have significant consequences for both malaria epidemiology and vector control. This stresses the need for understanding the combined effects of insecticide resistance and infection on the efficacy on control tools. specialized 052 9 art. 6664 [8 ] 2019 2045-2322 https://www.documentation.ird.fr/hor/fdi:010075655 10.1038/s41598-019-43195-6 2045-2322 [F B010075655] https://www.documentation.ird.fr/hor/fdi:010075655 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers19-05/010075655.pdf IRD - Base Horizon / Pleins textes 2019-06-04 2025-02-24 fdi:010075655 fre