Trung N. V. auteur aut IRD Hoi L. auteur aut IRD Dien V. M. auteur aut IRD Huong D. T. auteur aut IRD Hoa T. M. auteur aut IRD Lien V. N. auteur aut IRD Luan V. auteur aut IRD Lewycka S. O. auteur aut IRD Choisy Marc auteur aut IRD Bryant J. E. auteur aut IRD Nadjm B. auteur aut IRD Van Doorn H. R. auteur aut IRD Richards A. L. auteur aut IRD Van Kinh N. auteur aut IRD text journalArticle eng text/pdf reformatted digital access Rickettsioses are endemic to Vietnam; however, only a limited number of clinical studies have been performed on these vectorborne bacteria. We conducted a prospective hospital-based study at 2 national referral hospitals in Hanoi to describe the clinical characteristics of scrub typhus and murine typhus in northern Vietnam and to assess the diagnostic applicability of quantitative real-time PCR assays to diagnose rickettsia' diseases. We enrolled 302 patients with acute undifferentiated fever and clinically suspected rickettsiosis during March 2015-March 2017. We used a standardized case report form to collect clinical information and laboratory results at the time of admission and during treatment. We confirmed scrub typhus in 103 (34.1%) patients and murine typhus in 12 (3.3%) patients. These results highlight the need for increased emphasis on training for healthcare providers for earlier recognition, prevention, and treatment of rickettsial diseases in Vietnam. specialized VIET NAM 052 050 080 25 4 633-641 2019 1080-6040 https://www.documentation.ird.fr/hor/fdi:010075483 10.3201/eid2504.180691 1080-6040 [F B010075483] https://www.documentation.ird.fr/hor/fdi:010075483 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers19-04/010075483.pdf IRD - Base Horizon / Pleins textes 2019-05-13 2019-05-13 fdi:010075483 fre