Robert Vincent auteur aut IRD Molez Jean-François auteur aut IRD Trape Jean-François auteur aut IRD text journalArticle eng text/pdf reformatted digital access Patients with Plasmodium falciparum infections were selected with an in vivo chloroquine sensitivity assay. Fourteen days after treatment, the gametocytes were studied in relation to asexual parasite responses classified as drug-sensitive or showing RI or RII resistance. Gametocyte prevalence and density appeared significantly higher in RII than RI strains and higher in RI than in sensitive strains. This finding on gametocyte variation in vivo may explain why the RII type of chloroquine resistance has became more prevalent than RI everywhere in tropical Africa in the short time since its emergence. The biological and epidemiologic advantage of chloroquine-resistant malaria mediated through gametocytes is discussed in the context of the present drug pressure in Africa. specialized PALUDISME AGENT PATHOGENE SENSIBILITE RESISTANCE EPIDEMIOLOGIE PREVALENCE EFFICACITE TRAITEMENT MEDICAL CHLOROQUINE AFRIQUE DE L'OUEST SENEGAL DAKAR 052ANOPAL04 55 3 350-351 1996 0002-9637 https://www.documentation.ird.fr/hor/fdi:01007536 10.4269/ajtmh.1996.55.350 0002-9637 [F B010007536] https://www.documentation.ird.fr/hor/fdi:01007536 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/pleins_textes_6/b_fdi_45-46/010007536.pdf IRD - Base Horizon / Pleins textes 1996-11-22 2025-05-22 fdi:01007536 fre