@article{fdi:010075319,
  title = {{A} multi-country study of the economic burden of dengue fever based on patient-specific field surveys in {B}urkina {F}aso, {K}enya, and {C}ambodia},
  author = {{L}ee, {J}. {S}. and {M}ogasale, {V}. and {L}im, {J}. {K}. and {L}y, {S}. and {L}ee, {K}. {S}. and {S}orn, {S}. and {A}ndia, {E}. and {C}arabali, {M}. and {N}amkung, {S}. and {L}im, {S}. {K}. and {R}idde, {V}al{\'e}ry and {N}jenga, {S}. {M}. and {Y}aro, {S}. and {Y}oon, {I}. {K}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {D}engue fever is a rapidly growing public health problem in many parts of the tropics and sub-tropics in the world. {W}hile there are existing studies on the economic burden of dengue fever in some of dengue-endemic countries, cost components are often not standardized, making cross-country comparisons challenging. {F}urthermore, no such studies have been available in {A}frica. {M}ethods/{P}rincipal findings {A} patient-specific survey questionnaire was developed and applied in {B}urkina {F}aso, {K}enya, and {C}ambodia in a standardized format. {M}ultiple interviews were carried out in order to capture the entire cost incurred during the period of dengue illness. {B}oth private (patient's out-of-pocket) and public (non-private) expenditure were accessed to understand how the economic burden of dengue is distributed between private and non-private payers. {A} substantial number of dengue-confirmed patients were identified in all three countries: 414 in {B}urkina {F}aso, 149 in {K}enya, and 254 in {C}ambodia. {T}he average cost of illness for dengue fever was $26 (95% {CI} $23-$29) and $134 (95% {CI} $119-$152) per inpatient in {B}urkina {F}aso and {C}ambodia, respectively. {I}n the case of outpatients, the average economic burden per episode was $13 (95% {CI} $23-$29) in {B}urkina {F}aso and $23 (95% {CI} $19-$28) in {K}enya. {C}ompared to {C}ambodia, public contributions were trivial in {B}urkina {F}aso and {K}enya, reflecting that a majority of medical costs had to be directly borne by patients in the two countries. {C}onclusions/{S}ignificance {T}he cost of illness for dengue fever is significant in the three countries. {I}n particular, the current study sheds light on the potential economic burden of the disease in {B}urkina {F}aso and {K}enya where existing evidence is sparse in the context of dengue fever, and underscores the need to achieve {U}niversal {H}ealth {C}overage. {G}iven the availability of the current ({CYD}-{TDV}) and second-generation dengue vaccines in the near future, our study outcomes can be used to guide decision makers in setting health policy priorities. {A}uthor summary {D}engue fever is a major public health concern in many parts of {S}outh-{E}ast {A}sia and {S}outh {A}merica. {I}n addition to countries where dengue has been highly prevalent for many years, there is a growing concern on the undocumented burden of dengue in {A}frica. {F}ollowing the successful execution of the first-round economic burden study in {V}ietnam, {T}hailand, and {C}olombia by the {D}engue {V}accine {I}nitiative, the second-round economic burden study was implemented in {B}urkina {F}aso, {K}enya and {C}ambodia using the same standardized methodology. {I}n particular, the second-round study targeted {GAVI} eligible countries for future vaccine introductions and included two {A}frican countries where the burden of dengue was relatively unknown. {O}ur study outcomes show that the economic burden of dengue fever is significant in all three countries. {T}he dengue vaccination era began in 2016 with the first dengue vaccine ({CYD}-{TDV}) although its public use should be carefully determined due to the safety concerns related to the vaccine. {C}onsidering that there are other second-generation dengue vaccines in development, the current study outcomes provide an important step to estimate the economic benefits of vaccination in the three countries.},
  keywords = {{BURKINA} {FASO} ; {KENYA} ; {CAMBODGE}},
  booktitle = {},
  journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases},
  volume = {13},
  numero = {2},
  pages = {e0007164 [15 ]},
  ISSN = {1935-2735},
  year = {2019},
  DOI = {10.1371/journal.pntd.0007164},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075319},
}