@article{fdi:010075304,
  title = {{G}enomic evidence for shared common ancestry of {E}ast {A}frican hunting-gathering populations and insights into local adaptation},
  author = {{S}cheinfeldt, {L}. {B}. and {S}oi, {S}. and {L}ambert, {C}. and {K}o, {W}. {Y}. and {C}oulibaly, {A}. and {R}anciaro, {A}. and {T}hompson, {S}. and {H}irbo, {J}. and {B}eggs, {W}. and {I}brahim, {M}. and {N}yambo, {T}. and {O}mar, {S}. and {W}oldemeskel, {D}. and {B}elay, {G}. and {F}roment, {A}lain and {K}im, {J}. and {T}ishkoff, {S}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}natomically modern humans arose in {A}frica similar to 300,000 years ago, but the demographic and adaptive histories of {A}frican populations are not well-characterized. {H}ere, we have generated a genome-wide dataset from 840 {A}fricans, residing in western, eastern, southern, and northern {A}frica, belonging to 50 ethnicities, and speaking languages belonging to four language families. {I}n addition to agriculturalists and pastoralists, our study includes 16 populations that practice, or until recently have practiced, a hunting-gathering ({HG}) lifestyle. {W}e observe that genetic structure in {A}frica is broadly correlated not only with geography, but to a lesser extent, with linguistic affiliation and subsistence strategy. {F}our {E}ast {A}frican {HG} ({EHG}) populations that are geographically distant from each other show evidence of common ancestry: the {H}adza and {S}andawe in {T}anzania, who speak languages with clicks classified as {K}hoisan; the {D}ahalo in {K}enya, whose language has remnant clicks; and the {S}abue in {E}thiopia, who speak an unclassified language. {A}dditionally, we observed common ancestry between central {A}frican rainforest {HG}s and southern {A}frican {S}an, the latter of whom speak languages with clicks classified as {K}hoisan. {W}ith the exception of the {EHG}, central {A}frican rainforest {HG}s, and {S}an, other {HG} groups in {A}frica appear genetically similar to neighboring agriculturalist or pastoralist populations. {W}e additionally demonstrate that infectious disease, immune response, and diet have played important roles in the adaptive landscape of {A}frican history. {H}owever, while the broad biological processes involved in recent human adaptation in {A}frica are often consistent across populations, the specific loci affected by selective pressures more often vary across populations.},
  keywords = {{A}frican hunter-gatherers ; {A}frican diversity ; population genetics ; natural selection ; human evolution ; {AFRIQUE} {DE} {L}'{EST} ; {AFRIQUE} {SUBSAHARIENNE}},
  booktitle = {},
  journal = {{P}roceedings of the {N}ational {A}cademy of {S}ciences of the {U}nited {S}tates of {A}merica},
  volume = {116},
  numero = {10},
  pages = {4166--4175},
  ISSN = {0027-8424},
  year = {2019},
  DOI = {10.1073/pnas.1817678116},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075304},
}