@article{fdi:010075287, title = {{E}valuation of the efficacy and tolerance of {I}noserp ({R}) {P}anafricain in {S}enegal}, author = {{L}am, {A}. and {C}abral, {M}. and {T}oure, {A}. and {B}a, {F}. and {C}amara, {B}. and {K}ane, {O}. and {F}all, {M}. and {D}iouf, {A}. and {C}hippaux, {J}ean-{P}hilippe}, editor = {}, language = {{FRE}}, abstract = {{B}ackground. - {I}n {S}enegal, a sub-{S}ahara {A}frican country, snakebite represents a huge issue now considered as neglected disease. {O}bjective. - {T}he purpose of this study was to assess the efficacy and tolerance of {I}noserp ({R}) {P}anafrican antivenom in peripheral health structures. {M}ethod. - {A} management algorithm defined according to preliminary clinical studies was used. {R}esults. - {D}uring 20 months, 66 envenomed patients attended health centers, out of whom 63 treated by {I}noserp ({R}) {P}anafrican. {T}he population was representative of snake bitten patients in sub-{S}aharan {A}frica. {D}espite a high average treatment delay according to the level of the concerned health premises, and 25% of the recorded protocol deviations, this antivenom appeared to be effective and very well tolerated. {C}onclusions. - {O}ur results make it possible to envisage the implementation of the protocol of care at the national level and to reinforce the accessibility of the antivenins. {A}wareness and training of health professionals in the management of snakebites is essential to improve the evolution of envenomations. {T}he authors recommend to organize a pharmacovigilance network to evaluate the efficacy and safety of antivenoms.}, keywords = {{E}nvenomation ; {S}nakebite ; {A}ntivenom ; {I}noserp ({R}) {P}anafricain ; {A}frica ; {S}enegal ; {SENEGAL}}, booktitle = {}, journal = {{T}oxicologie {A}nalytique et {C}linique}, volume = {31}, numero = {1}, pages = {18--29}, ISSN = {2352-0078}, year = {2019}, DOI = {10.1016/j.toxac.2018.12.008}, URL = {https://www.documentation.ird.fr/hor/fdi:010075287}, }