@article{fdi:010075250, title = {{C}o-circulation and excretion dynamics of diverse rubula- and related viruses in egyptian rousette bats from {S}outh {A}frica}, author = {{M}ortlock, {M}. and {D}ietrich, {M}uriel and {W}eyer, {J}. and {P}aweska, {J}. {T}. and {M}arkotter, {W}.}, editor = {}, language = {{ENG}}, abstract = {{T}he {E}gyptian rousette bat ({R}ousettus aegyptiacus) has previously been implicated as the natural host of a zoonotic rubulavirus; however, its association with rubulaviruses has been studied to a limited extent. {U}rine, spleen, and other organs collected from the {R}. aegyptiacus population within {S}outh {A}frica were tested with a hemi-nested {RT}-{PCR} assay targeting a partial polymerase gene region of viruses from the {A}vula- and {R}ubulavirus genera. {U}rine was collected over a 14-month period to study the temporal dynamics of viral excretion. {D}iverse rubulaviruses, including viruses related to human mumps and parainfluenza virus 2, were detected. {A}ctive excretion was identified during two peak periods coinciding with the host reproductive cycle. {A}nalysis of additional organs indicated co-infection of individual bats with a number of different putative rubulaviruses, highlighting the limitations of using a single sample type when determining viral presence and diversity. {O}ur findings suggest that {R}. aegyptiacus can harbor a range of {R}ubula- and related viruses, some of which are related to known human pathogens. {T}he observed peaks in viral excretion represents potential periods of a higher risk of virus transmission and zoonotic disease spill-over.}, keywords = {paramyxovirus ; rubulavirus ; {E}gyptian rousette bat ; co-circulation ; viral ; shedding ; tissue distribution ; human mumps virus-related ; human ; parainfluenza virus-related ; excretion dynamics ; {AFRIQUE} {DU} {SUD}}, booktitle = {}, journal = {{V}iruses - {B}asel}, volume = {11}, numero = {1}, pages = {art. 37 [21 p.]}, ISSN = {1999-4915}, year = {2019}, DOI = {10.3390/v11010037}, URL = {https://www.documentation.ird.fr/hor/fdi:010075250}, }