@article{fdi:010075228,
  title = {{W}hat approaches are most effective at addressing micronutrient deficiency in children 0-5 years ? {A} review of systematic reviews},
  author = {{C}ampos {P}once, {M}. and {P}olman, {K}. and {R}oos, {N}. and {W}ieringa, {F}ranck and {B}erger, {J}acques and {D}oak, {C}. {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}ntroduction {E}ven though micronutrient deficiency is still a major public health problem, it is still unclear which interventions are most effective in improving micronutrient status. {T}his review therefore aims to summarize the evidence published in systematic reviews on intervention strategies that aim at improving micronutrient status in children under the age of five. {M}ethods {W}e searched the literature and included systematic reviews that reported on micronutrient status as a primary outcome for children of 0-5 years old, had a focus on low or middle income countries. {S}ubsequently, papers were reviewed and selected by two authors. {R}esults {W}e included 4235 reviews in this systematic review. {W}e found that (single or multiple) micronutrient deficiencies in pre-school children improved after providing (single or multiple) micronutrients. {H}owever home fortification did not always lead to significant increase in serum vitamin {A}, serum ferritin, hemoglobin or zinc. {C}ommercial fortification did improve iron status. {C}ord clamping reduced the risk of anemia in infants up to 6 months and, in helminth endemic areas, anthelminthic treatment increased serum ferritin levels, hemoglobin and improved height for age z-scores. {A}nti-malaria treatment improved ferritin levels. {D}iscussion {B}ased on our results the clearest recommendations are: delayed cord clamping is an effective intervention for reducing anemia in early life. {I}n helminth endemic areas iron status can be improved by anthelminthic treatment. {A}nti-malaria treatment can improve ferritin. {I}n deficient populations, single iron, vitamin {A} and multimicronutrient supplementation can improve iron, vitamin {A} and multimicronutrient status respectively. {W}hile the impact of home-fortification on multimicronutrient status remains questionable, commercial iron fortification may improve iron status.},
  keywords = {{M}icronutrient ; {D}eficiency ; {F}ortification ; {C}ord clamping ; {A}nthelmintics ; {A}nti-malaria treatment ; {ASIE} {DU} {SUD} {EST}},
  booktitle = {{I}mproving policies to combat micronutrient deficiencies in {S}outheast {A}sia : {T}he {SMILING} experience},
  journal = {{M}aternal and {C}hild {H}ealth {J}ournal},
  volume = {23},
  numero = {{S}uppl. 1 : no sp{\'e}cial},
  pages = {4--17},
  ISSN = {1092-7875},
  year = {2019},
  DOI = {10.1007/s10995-018-2527-9},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075228},
}