@article{fdi:010075153,
  title = {{R}esolving the apparent transmission paradox of {A}frican sleeping sickness},
  author = {{C}apewell, {P}. and {A}tkins, {K}. and {W}eir, {W}. and {J}amonneau, {V}incent and {C}amara, {M}. and {C}lucas, {C}. and {S}war, {N}. {R}. {K}. and {N}goyi, {D}. {M}. and {R}otureau, {B}. and {G}arside, {P}. and {G}alvani, {A}. {P}. and {B}ucheton, {B}runo and {M}ac{L}eod, {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}uman {A}frican trypanosomiasis ({HAT}), or {A}frican sleeping sickness, is a fatal disease found throughout sub-{S}aharan {A}frica. {T}he disease is close to elimination in many areas, although it was similarly close to elimination once before and subsequently reemerged, despite seemingly low rates of transmission. {D}etermining how these foci persisted and overcame an apparent transmission paradox is key to finally eliminating {HAT}. {B}y assessing clinical, laboratory, and mathematical data, we propose that asymptomatic infections contribute to transmission through the presence of an overlooked reservoir of skin-dwelling parasites. {O}ur assessment suggests that a combination of asymptomatic and parasitaemic cases is sufficient to maintain transmission at foci without animal reservoirs, and we argue that the current policy not to treat asymptomatic {HAT} should be reconsidered.},
  keywords = {{AFRIQUE} {SUBSAHARIENNE}},
  booktitle = {},
  journal = {{PL}o{S} {B}iology},
  volume = {17},
  numero = {1},
  pages = {e3000105 [6 p.]},
  ISSN = {1545-7885},
  year = {2019},
  DOI = {10.1371/journal.pbio.3000105},
  URL = {https://www.documentation.ird.fr/hor/fdi:010075153},
}