@article{fdi:010075131, title = {{D}etection of novel astroviruses among rodents of {G}abon, {C}entral {A}frica}, author = {{M}ombo, {I}. {M}. and {S}uquet, {E}. and {B}oundenga, {L}. and {M}veang-{N}zoghe, {A}. and {M}aganga-{M}boga, {C}. and {A}rnathau, {C}. and {S}idobre, {C}. and {L}eroy, {E}ric and {R}ougeron, {V}.}, editor = {}, language = {{ENG}}, abstract = {{A}stroviruses ({A}st{V}s) are mostly responsible for mild to severe gastroenteritis infections in humans and animals. {A}st{V}s infect a wide range of host species, have a large genetic diversity with different circulating variants and are thus a high zoonotic risk for human populations. {A}mong these host species, rodents are known to harbor several {A}st{V}s variants. {T}herefore, it is important to identify in rodent species which {A}st{V}s are circulating and evaluate their potential zoonotic risk for humans. {I}n this context, this study aimed to screen the presence of {A}st{V}s in 267 rodents trapped in 2012 in {F}ranceville and {M}akokou, two cities in {G}abon. {RNA} extracted from grinded intestines were used for the screening of {A}st{V}s by amplification of a conserved region of the {RNA} dependent {RNA} polymerase. {R}esults report the identification of {A}st{V}s in 12 individuals (4.6% rate), belonging to three different species including {R}attus rattus, {M}us musculus and {H}ybomys univittatus. {T}hese findings report the first identification of {A}st{V}s in {R}. rattus and {H}. univittatus. {T}he phylogenetic analyses indicate host specificity of rodents {A}st{V}s. {T}he absence of rodent {A}st{V}s within the human {A}st{V} {G}lade suggests a low rate of interspecies transmission of these viruses and consequently a low zoonotic risk.}, keywords = {{A}strovirus ; {R}odent ; {E}pidemiology ; {Z}oonotic risk ; {G}abon ; {GABON}}, booktitle = {}, journal = {{I}nfection {G}enetics and {E}volution}, volume = {68}, numero = {}, pages = {43--46}, ISSN = {1567-1348}, year = {2019}, DOI = {10.1016/j.meegid.2018.12.003}, URL = {https://www.documentation.ird.fr/hor/fdi:010075131}, }