@article{fdi:010074874, title = {{H}igh prevalence and diversity of hepatitis {B} and hepatitis delta virus in {G}abon}, author = {{G}roc, {S}. and {A}bbate, {J}. {L}. and {L}e {G}al, {F}. and {G}erber, {A}. and {T}uaillon, {E}. and {A}lbert, {J}. {L}. and {N}koghe, {D}. and {L}eroy, {E}ric and {R}oche, {B}enjamin and {B}ecquart, {P}ierre}, editor = {}, language = {{ENG}}, abstract = {{A}lthough central {A}frica is classified as having a high endemicity of hepatitis {B} virus ({HBV}) and hepatitis {D} virus ({HDV}) infection, there is paucity of prevalence studies. {F}or the first time on a country-wide level in {C}entral {A}frica, we show in {G}abon an overall 7.4% prevalence of {H}epatitis {B} surface antigen ({HB}s{A}g) and that more than 25% of the {HB}s{A}g-positive population are infected by {HDV}. {A}lthough {HBV} prevalence did not differ significantly between provinces, there is a north-south split in the distribution of {HDV} seroprevalence, with the highest rates (>66.0%) correlating with the presence of specific ethnic groups in the northeastern provinces. {G}enotyping revealed high genetic diversity of the {HBV} and {HDV} strains circulating in {G}abon, including many restricted to this region of the globe. {T}his work confirmed that high exposure to {HBV} and {HDV} infection reported in selected regions of {G}abon holds true across the whole country.}, keywords = {{G}abon ; genotype ; hepatitis {B} virus ; hepatitis {D} virus ; seroprevalence ; {GABON}}, booktitle = {}, journal = {{J}ournal of {V}iral {H}epatitis}, volume = {26}, numero = {1}, pages = {170--182}, ISSN = {1352-0504}, year = {2019}, DOI = {10.1111/jvh.12991}, URL = {https://www.documentation.ird.fr/hor/fdi:010074874}, }