@article{fdi:010074527,
  title = {16{S} metagenomic comparison of {P}lasmodium falciparum-infected and noninfected {A}nopheles gambiae and {A}nopheles funestus microbiota from {S}enegal},
  author = {{B}assene, {H}ubert and {N}iang, {E}. {A}. and {F}enollar, {F}. and {D}ipankar, {B}. and {D}oucour{\'e}, {S}ouleymane and {A}li, {E}. and {M}ichelle, {C}. and {R}aoult, {D}. and {S}okhna, {C}heikh and {M}ediannikov, {O}leg},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n the context of the pre-elimination of malaria, biological control may provide an alternative or additional tool to current malaria control strategies. {D}uring their various stages of development, mosquitoes undergo subsequent changes in their associated microbiota, depending on their environment and nutritional status. {A}lthough {A}nopheles gambiae s.l. and {A}nopheles funestus are the two major malaria vectors in {S}enegal, the composition of their microbiota is not yet well known. {I}n this study, we explored the microbiota of mosquitoes naturally infected or not by {P}lasmodium falciparum ({P}f) using the 16{S} ribosomal {RNA} gene-based bacterial metagenomic approach. {I}n both vector species, the microbiota was more diverse in {P}f-infected samples than in the noninfected ones, although the total number of reads appeared to be higher in noninfected mosquitoes. {O}verall, the microbiota was different between the two vector species. {N}oteworthy, the bacterial microbiota was significantly different between {P}f-positive and {P}f-negative groups whatever the species, but was similar between individuals of the same infection status within a species. {O}verall, the phylum of {P}roteobacteria was the most predominant in both species, with bacteria of the genus {B}urkholderia outweighing the others in noninfected vectors. {T}he presence of some specific bacterial species such as {A}saia bogorensis, {E}nterobacter cloacae, {B}urkholderia fungorum, and {B}urkholderia cepacia was also observed in {P}f-free samples only. {T}hese preliminary observations pave the way for further characterization of the mosquito microbiota to select promising bacterial candidates for potential use in an innovative approach to controlling malaria and overcoming the challenges to achieving a malaria-free world.},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {99},
  numero = {6},
  pages = {1489--1498},
  ISSN = {0002-9637},
  year = {2018},
  DOI = {10.4269/ajtmh.18-0263},
  URL = {https://www.documentation.ird.fr/hor/fdi:010074527},
}