@article{fdi:010074343,
  title = {{I}mplications of insecticide resistance for malaria vector control with long-lasting insecticidal nets : trends in pyrethroid resistance during a {WHO}-coordinated multi-country prospective study},
  author = {{C}ook, {J}. and {T}omlinson, {S}. and {K}leinschmidt, {I}. and {D}onnelly, {M}. {J}. and {A}kogbeto, {M}. and {A}dechoubou, {A}. and {M}assougbodji, {A}. and {O}ke-{S}opoh, {M}. and {C}orbel, {V}incent and {C}orn{\'e}lie, {S}ylvie and {O}gouyemi-{H}ounto, {A}. and {E}tang, {J}. and {A}wono-{A}mbene, {H}. {P}. and {B}igoga, {J}. and {M}andeng, {S}. {E}. and {N}jeambosay, {B}. and {T}abue, {R}. and {K}ouambeng, {C}. and {F}ondjo, {E}. and {R}aghavendra, {K}. and {B}hatt, {R}. {M}. and {C}hourasia, {M}. {K}. and {S}wain, {D}. {K}. and {U}ragayala, {S}. and {V}alecha, {N}. and {M}bogo, {C}. and {B}ayoh, {N}. and {K}inyari, {T}. and {N}jagi, {K}. and {M}uthami, {L}. and {K}amau, {L}. and {M}athenge, {E}. and {O}chomo, {E}. and {K}afy, {H}. {T}. and {I}smail, {B}. {A}. and {M}alik, {E}. {M}. and {E}lmardi, {K}. and {S}ulieman, {J}. {E}. and {A}bdin, {M}. and {S}ubramaniam, {K}. and {T}homas, {B}. and {W}est, {P}. and {B}radley, {J}. and {K}nox, {T}. {B}. and {M}nzava, {A}. {P}. and {L}ines, {J}. and {M}acdonaldand, {M}. and {N}kuni, {Z}. {J}. and {I}nsecticide {R}esistance {C}onsortium},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground{I}ncreasing pyrethroid resistance has been an undesirable correlate of the rapid increase in coverage of insecticide-treated nets ({ITN}s) since 2000. {W}hilst monitoring of resistance levels has increased markedly over this period, longitudinal monitoring is still lacking, meaning the temporal and spatial dynamics of phenotypic resistance in the context of increasing {ITN} coverage are unclear.{M}ethods{A}s part of a large {WHO}-co-ordinated epidemiological study investigating the impact of resistance on malaria infection, longitudinal monitoring of phenotypic resistance to pyrethroids was undertaken in 290 clusters across {B}enin, {C}ameroon, {I}ndia, {K}enya and {S}udan. {M}ortality in response to pyrethroids in the major anopheline vectors in each location was recorded during consecutive years using standard {WHO} test procedures. {T}rends in mosquito mortality were examined using generalised linear mixed-effect models.{R}esults{I}nsecticide resistance (using the {WHO} definition of mortality < 90%) was detected in clusters in all countries across the study period. {T}he highest mosquito mortality (lowest resistance frequency) was consistently reported from {I}ndia, in an area where {ITN}s had only recently been introduced. {S}ubstantial temporal and spatial variation was evident in mortality measures in all countries. {O}verall, a trend of decreasing mosquito mortality (increasing resistance frequency) was recorded ({O}dds {R}atio per year: 0.79 per year (95% {CI}: 0.79-0.81, {P} < 0.001). {T}here was also evidence that higher net usage was associated with lower mosquito mortality in some countries.{D}iscussion{P}yrethroid resistance increased over the study duration in four out of five countries. {I}nsecticide-based vector control may be compromised as a result of ever higher resistance frequencies.},
  keywords = {{M}alaria ; {V}ector control ; {I}nsecticide resistance ; {T}rends ; {B}ednets ; {B}ioassay ; {BENIN} ; {CAMEROUN} ; {KENYA} ; {SOUDAN} ; {INDE}},
  booktitle = {},
  journal = {{P}arasites and {V}ectors},
  volume = {11},
  numero = {},
  pages = {art. 550 [10 p.]},
  ISSN = {1756-3305},
  year = {2018},
  DOI = {10.1186/s13071-018-3101-4},
  URL = {https://www.documentation.ird.fr/hor/fdi:010074343},
}