%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Sigh, S. %A Roos, N. %A Chamnan, C. %A Laillou, A. %A Prak, S. %A Wieringa, Franck %T Effectiveness of a locally produced, fish-based food product on weight gain among Cambodian children in the treatment of acute malnutrition : a randomized controlled trial %D 2018 %L fdi:010074321 %G ENG %J Nutrients %@ 2072-6643 %K severe acute malnutrition ; fish ; ready-to-use therapeutic foods ; effectiveness ; weight gain ; Cambodia %K CAMBODGE %M ISI:000447544900112 %N 7 %P art. 909 [17 ] %R 10.3390/nu10070909 %U https://www.documentation.ird.fr/hor/fdi:010074321 %> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers18-11/010074321.pdf %V 10 %W Horizon (IRD) %X Cambodia continues to have a high prevalence of acute malnutrition. Low acceptability has been found for standard ready-to-use-therapeutic-food (RUTF) products. Therefore, NumTrey, a locally-produced fish-based RUTF, was developed. The objective was to evaluate the effectiveness of NumTrey compared to an imported milk-based RUTF for weight gain among children aged 6-59 months in the home-treatment for acute malnutrition. Effectiveness was tested in a single-blinded randomized controlled trial with weight gain as the primary outcome. Anthropometry was assessed at baseline and bi-weekly follow-ups until endline at Week 8. In total, 121 patients were randomized into BP-100(TM) (n = 61) or NumTrey (n = 60). There was no statistical difference in mean weight gain between the groups (1.06 g/kg/day; 95% CI (0.72, 1.41) and 1.08 g/kg/day; 95% CI (0.75, 1.41) for BP-100 and NumTrey, respectively). In addition, no statistically significant differences in secondary outcomes were found. Although the ability to draw conclusions was limited by lower weight gain than the desired 4 g/kg/day in both groups, no superiority was found for eitherRUTF. A locally produced RUTF is highly relevant to improve nutrition interventions in Cambodia. A locally produced fish-based RUTF is a relevant alternative to imported milk-based RUTF for the treatment of SAM in Cambodia. %$ 054