@article{fdi:010074158,
  title = {{T}oxics ({P}b, {C}d) and trace elements ({Z}n, {C}u, {M}n) in women during pregnancy and at delivery, {S}outh {B}enin, 2014-2015},
  author = {{G}uy, {M}. and {A}ccrombessi, {M}. and {F}ievet, {N}adine and {Y}ovo, {E}. and {M}assougbodji, {A}. and {L}e {B}ot, {B}. and {G}lorennec, {P}. and {B}odeau-{L}ivinec, {F}. and {B}riand, {V}al{\'e}rie},
  editor = {},
  language = {{ENG}},
  abstract = {{D}uring pregnancy, fetal development can be hindered by maternal exposure to toxic elements and abnormal concentrations of trace elements. {F}ew data are available in {A}frican countries. {O}ur goal was to assess the body burden of lead ({P}b), cadmium ({C}d), manganese ({M}n), zinc ({Z}n) and copper ({C}u) in pregnant women in {B}enin. {T}he study was carried out in {S}o-{A}va district, from {N}ovember 2015 to {A}pril 2016. {S}ixty women were recruited from the {RECIPAL} pre-conceptional cohort study. {I}n all women, blood samples were collected during the first trimester of pregnancy. {T}hirty-two women had additional maternal and cord blood samples collected at delivery. {B}lood samples were analyzed by inductively coupled plasma mass spectrometry. {A}t delivery, {C}d median ({IQR}) concentration in maternal blood was 0.34 mu g/{L} (0.24-0.46) in this non-smoking population. {P}b median ({IQR}) concentration in maternal blood at delivery was 37.4 mu g/{L} (30.5-52.0), with 31.3% of blood {P}b levels above the 50 mu pg/{L} threshold. {T}hese pregnant women lived in semi-rural lakeside villages. {P}otential sources of {P}b exposure identified during pregnancy were having water supply by drill pump and activities such as smoking fish by the woman and fishing by the household head. {A}t delivery, {Z}n, {C}u, and {M}n median ({IQR}) concentrations in maternal blood were, respectively, 5415 mu g/{L} (4894-5822), 1609 mu g/{L} (1295-1771) and 16.0 mu g/{L} (12.5-20.8). {P}b, {C}d, {M}n and {C}u blood concentrations were significantly higher at delivery than during the first trimester of pregnancy. {P}b, {C}d, {Z}n and {C}u concentrations were significantly lower in cord blood than in maternal blood, contrary to {M}n concentration, which was significantly higher in cord blood than in maternal blood at delivery. {T}his exploratory study is the first one performed in {B}enin, and warns us about exposition of women from {S} (o) over cap -{A}va district to {P}b and {C}d during pregnancy.},
  keywords = {{E}nvironmental pollutants ; {T}race elements ; {P}regnancy ; {B}enin ; {P}ublic health ; {BENIN}},
  booktitle = {},
  journal = {{E}nvironmental {R}esearch},
  volume = {167},
  numero = {},
  pages = {198--206},
  ISSN = {0013-9351},
  year = {2018},
  DOI = {10.1016/j.envres.2018.06.054},
  URL = {https://www.documentation.ird.fr/hor/fdi:010074158},
}