@article{fdi:010074053, title = {{P}opulation structure of a vector of human diseases : {A}edes aegypti in its ancestral range, {A}frica}, author = {{K}otsakiozi, {P}. and {E}vans, {B}. {R}. and {G}loria-{S}oria, {A}. and {K}amgang, {B}. and {M}ayanja, {M}. and {L}utwama, {J}. and {L}e {G}off, {G}ilbert and {A}yala, {D}iego and {P}aupy, {C}hristophe and {B}adolo, {A}. and {P}into, {J}. and {S}ousa, {C}. {A}. and {T}roco, {A}. {D}. and {P}owell, {J}. {R}.}, editor = {}, language = {{ENG}}, abstract = {{A}edes aegypti, the major vector of dengue, yellow fever, chikungunya, and {Z}ika viruses, remains of great medical and public health concern. {T}here is little doubt that the ancestral home of the species is {A}frica. {T}his mosquito invaded the {N}ew {W}orld 400-500years ago and later, {A}sia. {H}owever, little is known about the genetic structure and history of {A}e.aegypti across {A}frica, as well as the possible origin(s) of the {N}ew {W}orld invasion. {H}ere, we use similar to 17,000 genome-wide single nucleotide polymorphisms ({SNP}s) to characterize a heretofore undocumented complex picture of this mosquito across its ancestral range in {A}frica. {W}e find signatures of human-assisted migrations, connectivity across long distances in sylvan populations, and of local admixture between domestic and sylvan populations. {F}inally, through a phylogenetic analysis combined with the genetic structure analyses, we suggest {W}est {A}frica and especially {A}ngola as the source of the {N}ew {W}orld's invasion, a scenario that fits well with the historic record of 16th-century slave trade between {A}frica and {A}mericas.}, keywords = {{A}edes aegypti ; {A}frica ; genetics ; migration ; population structure ; {SNP}-chip ; {AFRIQUE} {SUBSAHARIENNE} ; {ASIE} ; {AMERIQUE} {LATINE}}, booktitle = {}, journal = {{E}cology and {E}volution}, volume = {8}, numero = {16}, pages = {7835--7848}, ISSN = {2045-7758}, year = {2018}, DOI = {10.1002/ece3.4278}, URL = {https://www.documentation.ird.fr/hor/fdi:010074053}, }