Unguiculins A-C : cytotoxic bis-guanidine alkaloids from the French Polynesian sponge, Monanchora n. sp. El-Demerdash, A. Moriou, C. Martin, M. T. /Petek, Sylvain /Debitus, Cécile Al-Mourabit, A. Monanchora Crambeidae unguiculin guanidine spermidine alkaloid Two new acyclic bis-guanidine alkaloids, unguiculins B-C (2-3), were isolated from a French Polynesian sponge Monanchora n. sp. together with the known compound unguiculin A (1). Their structures were established by spectroscopic data interpretation and comparison with the literature. Unguiculins A-C displayed antiproliferative and cytotoxic efficacy against several human cancer cells with IC50 values in the micromolar range. [GRAPHICS] . 2018 text https://www.documentation.ird.fr/hor/fdi:010073062 fdi:010073062 El-Demerdash A., Moriou C., Martin M. T., Petek Sylvain, Debitus Cécile, Al-Mourabit A.. Unguiculins A-C : cytotoxic bis-guanidine alkaloids from the French Polynesian sponge, Monanchora n. sp.. 2018, 32 (13), 1512-1517 EN PACIFIQUE POLYNESIE FRANCAISE