Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru : a preliminary report
Machicado, C.
/Bertani, Stéphane
Herrera-Velit, P.
Espinoza, J.
Ruiz, E.
Marcos, L.
Cholangiocarcinoma
Fasciolosis
Fibrosis
Hepatocellular carcinoma
Liver fluke
Introduction: The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. Methods: In total, 13 scrum samples from 13 HCC patients were screened using Fas2-ELISA. Results: Fas2-ELISA demonstrated negative results in all HCC patients included in this study. Conclusions: The pre-existence of F hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
2018
text
https://www.documentation.ird.fr/hor/fdi:010073026
oai:ird.fr:fdi:010073026
Machicado C., Bertani Stéphane, Herrera-Velit P., Espinoza J., Ruiz E., Marcos L.. Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru : a preliminary report. 2018, 51 (2), 231-233
EN
PEROU