@article{fdi:010072814,
  title = {{P}otential biotechnological assets related to plant immunity modulation applicable in engineering disease-resistant crops},
  author = {{S}ilva, {M}. {S}. and {A}rraes, {F}. {B}. {M}. and {C}ampos, {M}. {D}. and {G}rossi-de-{S}a, {M}. and {F}ernandez, {D}iana and {C}andido, {E}. {D}. and {C}ardoso, {M}. {H}. and {F}ranco, {O}. {L}. and {G}rossi-de-{S}a, {M}. {F}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}his review emphasizes the biotechnological potential of molecules implicated in the different layers of plant immunity, including, pathogen-associated molecular pattern ({PAMP})-triggered immunity ({PTI}), effector-triggered susceptibility ({ETS}), and effector-triggered immunity ({ETI}) that can be applied in the development of disease-resistant genetically modified ({GM}) plants. {T}hese biomolecules are produced by pathogens (viruses, bacteria, fungi, oomycetes) or plants during their mutual interactions. {B}iomolecules involved in the first layers of plant immunity, {PTI} and {ETS}, include inhibitors of pathogen cell-wall-degrading enzymes ({CWDE}s), plant pattern recognition receptors ({PRR}s) and susceptibility ({S}) proteins, while the {ETI}-related biomolecules include plant resistance ({R}) proteins. {T}he biomolecules involved in plant defense {PTI}/{ETI} responses described herein also include antimicrobial peptides ({AMP}s), pathogenesis-related ({PR}) proteins and ribosome-inhibiting proteins ({RIP}s), as well as enzymes involved in plant defensive secondary metabolite biosynthesis (phytoanticipins and phytoalexins). {M}oreover, the regulation of immunity by {RNA} interference ({RNA}i) in {GM} disease-resistant plants is also considered. {T}herefore, the present review does not cover all the classes of biomolecules involved in plant innate immunity that may be applied in the development of disease-resistant {GM} crops but instead highlights the most common strategies in the literature, as well as their advantages and disadvantages.},
  keywords = {{P}athogen-associated molecular pattern-triggered immunity ({PTI}) ; {E}ffector-triggered susceptibility ({ETS}) ; {E}ffector-triggered immunity ; ({ETI}) ; {RNA} interference ; {G}enetically modified ({GM}) crop ; {D}isease resistance},
  booktitle = {},
  journal = {{P}lant {S}cience},
  volume = {270},
  numero = {},
  pages = {72--84},
  ISSN = {0168-9452},
  year = {2018},
  DOI = {10.1016/j.plantsci.2018.02.013},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072814},
}