@article{fdi:010072740,
  title = {{A} seven-year retrospective study on the surveillance of hepatitis {B} in {L}aos},
  author = {{P}aboriboune, {P}. and {V}ial, {T}homas and {C}hassagne, {F}. and {S}itbounlang, {P}. and {S}oundala, {S}. and {B}ertani, {S}t{\'e}phane and {S}engmanothong, {D}. and {B}abin, {F}. {X}. and {S}teenkeste, {N}. and {D}eny, {P}. and {P}ineau, {P}. and {D}eharo, {E}ric},
  editor = {},
  language = {{ENG}},
  abstract = {{O}bjective. {L}ao {PDR} is one of the most highly endemic countries for hepatitis {B} in {A}sia and the second country for liver cancer incidence. {T}herefore, the follow-up of infected individuals through predictive serological markers is of utmost importance to monitor the progression of the pathology and take the decision on treatment. {M}ethods. {A} retrospective-descriptive cohort study was conducted on 3,857 {HBV}-infected patients. {I}nformation about infection status (viral load, {VL}), liver function (aminotransferases), and treatments was recorded. {R}esults. {M}/{F} sex ratio was 1.77 for a median age of 37. {P}atients under 37 displayed higher {VL} than older ones and men had higher {VL} than women. {I}nitial {VL} ranged from <50 {IU}/m{L} to 2.5 10(13) {IU}/m{L}. {M}edian aminotransferase values were 45.5 {U}/{L} for {ALAT} and 44 {U}/{L} for {ASAT}, ranging from <8 to >2,000 {U}/{L}. {M}en had higher aminotransferase than women. {G}lobally 20% of patients received treatment (mainly immunostimulant and reverse-transcriptase inhibitors); 11% had high levels of {VL} and liver enzymes, but only 2% of them were treated. {C}onclusion. {P}ublic health decisions should be taken urgently to rationalise vaccination and provide fair access to early diagnosis and treatment; otherwise the burden of {HBV}-associated diseases will be overwhelming for {L}aos in the near future.},
  keywords = {{LAOS}},
  booktitle = {},
  journal = {{I}nternational {J}ournal of {H}epatology},
  numero = {},
  pages = {art. {ID} 9462475 [11 p.]},
  ISSN = {2090-3448},
  year = {2018},
  DOI = {10.1155/2018/9462475},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072740},
}