Le Croizier G. auteur aut IRD Lacroix C. auteur aut IRD Artigaud S. auteur aut IRD Le Floch S. auteur aut IRD Raffray Jean auteur aut IRD Penicaud V. auteur aut IRD Coquille V. auteur aut IRD Autier J. auteur aut IRD Rouget M. L. auteur aut IRD Le Bayon N. auteur aut IRD Laë Raymond auteur aut IRD Tito de Morais Luis auteur aut IRD text journalArticle eng text/pdf born digital access Impacted marine environments lead to metal accumulation in edible marine fish, ultimately impairing human health. Nevertheless, metal accumulation is highly variable among marine fish species. In addition to ecological features, differences in bioaccumulation can be attributed to species-related physiological processes, which were investigated in two marine fish present in the Canary Current Large Marine Ecosystem (CCLME), where natural and anthropogenic metal exposure occurs. The European sea bass Dicentrarchus labrax and Senegalese sole Solea senegalensis were exposed for two months to two environmentally realistic dietary cadmium (Cd) doses before a depuration period. Organotropism (i.e., Cd repartition between organs) was studied in two storage compartments (the liver and muscle) and in an excretion vector (bile). To better understand the importance of physiological factors, the significance of hepatic metallothionein (MT) concentrations in accumulation and elimination kinetics in the two species was explored. Accumulation was faster in the sea bass muscle and liver, as inferred by earlier Cd increase and a higher accumulation rate. The elimination efficiency was also higher in the sea bass liver compared to sole, as highlighted by greater biliary excretion. In the liver, no induction of MT synthesis was attributed to metal exposure, challenging the relevance of using MT concentration as a biomarker of metal contamination. However, the basal MT pools were always greater in the liver of sea bass than in sole. This species-specific characteristic might have enhanced Cd biliary elimination and relocation to other organs such as muscle through the formation of more Cd/MT complexes. Thus, MT basal concentrations seem to play a key role in the variability observed in terms of metal concentrations in marine fish species. specialized Metal Trace element Dicentrarchus labrax Solea senegalensis Chronic dietary exposure 038 034 236 462-476 2018 0269-7491 https://www.documentation.ird.fr/hor/fdi:010072702 10.1016/j.envpol.2018.01.002 0269-7491 [F B010072702] https://www.documentation.ird.fr/hor/fdi:010072702 https://www.documentation.ird.fr/intranet/publi/2018/04/010072702.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2018-05-04 2023-07-11 fdi:010072702 fre