@article{fdi:010072369, title = {{D}ramatic changes in malaria population genetic complexity in {D}ielmo and {N}diop, {S}enegal, revealed using genomic surveillance}, author = {{B}ei, {A}. {K}. and {N}iang, {M}. and {D}eme, {A}. {B}. and {D}aniels, {R}. {F}. and {S}arr, {F}. {D}. and {S}okhna, {C}heikh and {T}alla, {C}. and {F}aye, {J}. and {D}iagne, {N}. and {D}oucoure, {S}. and {M}boup, {S}. and {W}irth, {D}. {F}. and {T}all, {A}. and {N}diaye, {D}. and {H}artl, {D}. {L}. and {V}olkman, {S}. {K}. and {T}oure-{B}alde, {A}.}, editor = {}, language = {{ENG}}, abstract = {{D}ramatic changes in transmission intensity can impact {P}lasmodium population diversity. {U}sing samples from 2 distant time-points in the {D}ielmo/{N}diop longitudinal cohorts from {S}enegal, we applied a molecular barcode tool to detect changes in parasite genotypes and complexity of infection that corresponded to changes in transmission intensity. {W}e observed a striking statistically significant difference in genetic diversity between the 2 parasite populations. {F}urthermore, we identified a genotype in {D}ielmo and {N}diop previously observed in {T}hies, potentially implicating imported malaria. {T}his genetic surveillance study validates the molecular barcode as a tool to assess parasite population diversity changes and track parasite genotypes.}, keywords = {malaria ; {D}ielmo/{N}diop ; {S}enegal ; genomic surveillance ; molecular barcode ; {SENEGAL} ; {DIELMO} ; {NDIOP}}, booktitle = {}, journal = {{J}ournal of {I}nfectious {D}iseases}, volume = {217}, numero = {4}, pages = {622--627}, ISSN = {0022-1899}, year = {2018}, DOI = {10.1093/infdis/jix580}, URL = {https://www.documentation.ird.fr/hor/fdi:010072369}, }