@article{fdi:010072339,
  title = {{T}ectus niloticus ({T}egulidae, {G}astropod) as a novel vector of ciguatera poisoning : detection of {P}acific ciguatoxins in toxic samples from {N}uku {H}iva {I}sland ({F}rench {P}olynesia)},
  author = {{D}arius, {H}. {T}. and {R}ou{\'e}, {M}elanie and {S}ibat, {M}. and {V}iallon, {J}. and {G}atti, {C}. {M}. {I}. and {V}andersea, {M}. {W}. and {T}ester, {P}. {A}. and {L}itaker, {R}. {W}. and {A}mzil, {Z}. and {H}ess, {P}. and {C}hinain, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}iguatera fish poisoning ({CFP}) is a foodborne disease caused by the consumption of seafood (fish and marine invertebrates) contaminated with ciguatoxins ({CTX}s) produced by dinoflagellates in the genus {G}ambierdiscus. {T}he report of a {CFP}-like mass-poisoning outbreak following the consumption of {T}ectus niloticus ({T}egulidae, {G}astropod) from {A}naho {B}ay on {N}uku {H}iva {I}sland ({M}arquesas archipelago, {F}rench {P}olynesia) prompted field investigations to assess the presence of {CTX}s in {T}. niloticus. {S}amples were collected from {A}naho {B}ay, 1, 6 and 28 months after this poisoning outbreak, as well as in {T}aiohae and {T}aipivai bays. {T}oxicity analysis using the neuroblastoma cell-based assay ({CBA}-{N}2a) detected the presence of {CTX}s only in {A}naho {B}ay {T}. niloticus samples. {T}his is consistent with q{PCR} results on window screen samples indicating the presence of {G}ambierdiscus communities dominated by the species {G}. polynesiensis in {A}naho {B}ay. {L}iquid chromatography-tandem mass spectrometry ({LC}-{MS}/{MS}) analyses revealed that {P}-{CTX}-3{B} was the major congener, followed by {P}-{CTX}-3{C}, {P}-{CTX}-4{A} and {P}-{CTX}-4{B} in toxic samples. {B}etween {J}uly 2014 and {N}ovember 2016, toxin content in {T}. niloticus progressively decreased, but was consistently above the safety limit recommended for human consumption. {T}his study confirms for the first time {T}. niloticus as a novel vector of {CFP} in {F}rench {P}olynesia.},
  keywords = {ciguatera poisoning ; ciguatoxins ; {T}ectus niloticus ; gastropods ; {G}ambierdiscus polynesiensis ; q{PCR} assays ; {CBA}-{N}2a ; {LC}-{MS} ; {MS} ; {PACIFIQUE} ; {POLYNESIE} {FRANCAISE} ; {NUKU} {HIVA} {ILE}},
  booktitle = {},
  journal = {{T}oxins},
  volume = {10},
  numero = {1},
  pages = {2},
  ISSN = {2072-6651},
  year = {2018},
  DOI = {10.3390/toxins10010002},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072339},
}