@article{fdi:010072009,
  title = {{M}etagenomic-based impact study of transgenic grapevine rootstock on its associated virome and soil bacteriome},
  author = {{H}ily, {J}. {M}. and {D}emaneche, {S}. and {P}oulicard, {N}ils and {T}annieres, {M}. and {D}jennane, {S}. and {B}euve, {M}. and {V}igne, {E}. and {D}emangeat, {G}. and {K}omar, {V}. and {G}ertz, {C}. and {M}armonier, {A}. and {H}emmer, {C}. and {V}igneron, {S}. and {M}arais, {A}. and {C}andresse, {T}. and {S}imonet, {P}. and {L}emaire, {O}.},
  editor = {},
  language = {{ENG}},
  abstract = {{F}or some crops, the only possible approach to gain a specific trait requires genome modification. {T}he development of virus-resistant transgenic plants based on the pathogen-derived resistance strategy has been a success story for over three decades. {H}owever, potential risks associated with the technology, such as horizontal gene transfer ({HGT}) of any part of the transgene to an existing gene pool, have been raised. {H}ere, we report no evidence of any undesirable impacts of genetically modified ({GM}) grapevine rootstock on its biotic environment. {U}sing state of the art metagenomics, we analysed two compartments in depth, the targeted {G}rapevine fanleaf virus ({GFLV}) populations and nontargeted root-associated microbiota. {O}ur results reveal no statistically significant differences in the genetic diversity of bacteria that can be linked to the {GM} trait. {I}n addition, no novel virus or bacteria recombinants of biosafety concern can be associated with transgenic grapevine rootstocks cultivated in commercial vineyard soil under greenhouse conditions for over 6 years.},
  keywords = {environmental microbiology ; metagenomics ; grapevine ; transgenic ; rootstock ; safety and regulatory affairs},
  booktitle = {},
  journal = {{P}lant {B}iotechnology {J}ournal},
  volume = {16},
  numero = {1},
  pages = {208--220},
  ISSN = {1467-7644},
  year = {2018},
  DOI = {10.1111/pbi.12761},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072009},
}