@article{fdi:010072002,
  title = {{G}enome-wide association study reveals candidate genes influencing lipids and diterpenes contents in {C}offea arabica {L}},
  author = {{S}ant'{A}na, {G}. {C}. and {P}ereira, {L}. {F}. {P}. and {P}ot, {D}. and {I}vamoto, {S}. {T}. and {D}omingues, {D}. {S}. and {F}erreira, {R}. {V}. and {P}agiatto, {N}. {F}. and da {S}ilva, {B}. {S}. {R}. and {N}ogueira, {L}. {M}. and {K}itzberger, {C}. {S}. {G}. and {S}cholz, {M}. {B}. {S}. and de {O}liveira, {F}. {F}. and {S}era, {G}. {H}. and {P}adilha, {L}. and {L}abouisse, {J}. {P}. and {G}uyot, {R}omain and {C}harmetant, {P}. and {L}eroy, {T}.},
  editor = {},
  language = {{ENG}},
  abstract = {{L}ipids, including the diterpenes cafestol and kahweol, are key compounds that contribute to the quality of coffee beverages. {W}e determined total lipid content and cafestol and kahweol concentrations in green beans and genotyped 107 {C}offea arabica accessions, including wild genotypes from the historical {FAO} collection from {E}thiopia. {A} genome-wide association study was performed to identify genomic regions associated with lipid, cafestol and kahweol contents and cafestol/kahweol ratio. {U}sing the diploid {C}offea canephora genome as a reference, we identified 6,696 {SNP}s. {P}opulation structure analyses suggested the presence of two to three groups ({K} = 2 and {K} = 3) corresponding to the east and west sides of the {G}reat {R}ift {V}alley and an additional group formed by wild accessions collected in western forests. {W}e identified 5 {SNP}s associated with lipid content, 4 with cafestol, 3 with kahweol and 9 with cafestol/kahweol ratio. {M}ost of these {SNP}s are located inside or near candidate genes related to metabolic pathways of these chemical compounds in coffee beans. {I}n addition, three trait-associated {SNP}s showed evidence of directional selection among cultivated and wild coffee accessions. {O}ur results also confirm a great allelic richness in wild accessions from {E}thiopia, especially in accessions originating from forests in the west side of the {G}reat {R}ift {V}alley.},
  keywords = {{ETIOPIE}},
  booktitle = {},
  journal = {{S}cientific {R}eports - {N}ature},
  volume = {8},
  numero = {},
  pages = {art. 465 [ 12 p.]},
  ISSN = {2045-2322},
  year = {2018},
  DOI = {10.1038/s41598-017-18800-1},
  URL = {https://www.documentation.ird.fr/hor/fdi:010072002},
}