@article{fdi:010071391, title = {{H}uman {A}frican trypanosomiasis}, author = {{B}uscher, {P}. and {C}ecchi, {G}. and {J}amonneau, {V}incent and {P}riotto, {G}.}, editor = {}, language = {{ENG}}, abstract = {{H}uman {A}frican trypanosomiasis (sleeping sickness) is a parasitic infection that almost invariably progresses to death unless treated. {H}uman {A}frican trypanosomiasis caused devastating epidemics during the 20th century. {T}hanks to sustained and coordinated efforts over the past 15 years, the number of reported cases has fallen to an historically low level. {F}ewer than 3000 cases were reported in 2015, and the disease is targeted for elimination by {WHO}. {D}espite these recent successes, the disease is still endemic in parts of sub-{S}aharan {A}frica, where it is a considerable burden on rural communities, most notably in central {A}frica. {S}ince patients are also reported from non-endemic countries, human {A}frican trypanosomiasis should be considered in differential diagnosis for travellers, tourists, migrants, and expatriates who have visited or lived in endemic areas. {I}n the absence of a vaccine, disease control relies on case detection and treatment, and vector control. {A}vailable drugs are suboptimal, but ongoing clinical trials provide hope for safer and simpler treatments.}, keywords = {{AFRIQUE} {SUBSAHARIENNE} ; {ZONE} {TROPICALE}}, booktitle = {}, journal = {{L}ancet}, volume = {390}, numero = {art. 10110 [13 p.]}, pages = {2397--2409}, ISSN = {0140-6736}, year = {2017}, DOI = {10.1016/s0140-6736(17)31510-6}, URL = {https://www.documentation.ird.fr/hor/fdi:010071391}, }