Leman-Loubière C. auteur aut IRD Le Goff G. auteur aut IRD Retailleau P. auteur aut IRD Debitus Cécile auteur aut IRD Ouazzani J. auteur aut IRD text journalArticle eng text/pdf born digital access Two sporothriolide-related compounds were obtained from an extract of the fungus Hypoxylon monticulosum CLL-205, isolated from a Sphaerocladina sponge collected from the Tahiti coast. Compound 2 is a deoxy analogue of sporothric acid (4). Compound 3 is a newly reported unusual scaffold combining sporothriolide (1) and trienylfuranol A (5) moieties, through a Diels-Alderase-type reaction. Various experimental and analytical arguments supported the biocatalytic origin of compound 3. The structures of the isolated compounds were elucidated using 1D and 2D NMR, HRMS, and IR data. The structure and the absolute configuration of 3 were unambiguously confirmed by a single-crystal X-ray diffraction analysis. specialized TAHITI PACIFIQUE 035 80 10 2850-2854 2017 0163-3864 https://www.documentation.ird.fr/hor/fdi:010071353 10.1021/acs.jnatprod.7b00714 0163-3864 [F B010071353] https://www.documentation.ird.fr/hor/fdi:010071353 https://www.documentation.ird.fr/intranet/publi/2017/11/010071353.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2017-12-04 2023-07-11 fdi:010071353 fre