%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Ahuka-Mundeke, S.
%A Mbala-Kingebeni, P.
%A Ndimbo-Kumogo, S. P.
%A Foncelle, C.
%A Lunguya-Metila, O.
%A Muyembe-Tamfum, J. J.
%A Delaporte, Eric
%A Peeters, Martine
%A Ayouba, Ahidjo
%T Full genome characterization of a new simian immune deficiency virus lineage in a naturally infected cercopithecus ascanius whitesidei in the Democratic Republic of Congo reveals high genetic diversity among red-tailed monkeys in Central and Eastern Africa
%D 2017
%L fdi:010070322
%G ENG
%J AIDS Research and Human Retroviruses
%@ 0889-2229
%K SIV ; HIV ; Cercopithecus ascanius ; red-tailed monkey ; Democratic Republic of Congo
%K REPUBLIQUE DEMOCRATIQUE DU CONGO
%M ISI:000404995300015
%N 7
%P 735-739
%R 10.1089/aid.2017.0027
%U https://www.documentation.ird.fr/hor/fdi:010070322
%> https://www.documentation.ird.fr/intranet/publi/2017/08/010070322.pdf
%V 33
%W Horizon (IRD)
%X Our knowledge on simian immune deficiency virus (SIV) diversity and evolution in the different nonhuman primate species is still incomplete. In this study, we report the full genome characterization of a new SIV from a red-tailed monkey (2013DRC-I8), from the Cercopithecus ascanius whitesidei subspecies, in the Democratic Republic of Congo (DRC). The new full-length genome is 9,926bp long, and the genomic structure is similar to that of other SIVs with the absence of vpx and vpu genes. The new SIVasc-13DRC-I8 strain fell within the Cercopithecus specific SIV lineage. SIVasc-13DRC-I8 and previously reported SIVrtg from the C.a. schmidti subspecies in Uganda did not form a separate species-specific SIV lineage. These observations provide additional evidence for high genetic diversity and the complex evolution of SIVs in the Cercopithecus genus. More studies on a large number of monkeys from a wider geographic area are needed to understand SIV evolution.
%$ 052 ; 080